T. Yoshizaki, Shinobu Minatani, Hiroto Namba, Akitoshi Takeda, J. Kawabe, Hideko Mizuta, Yasuhiro Wada, A. Mawatari, Yasuyoshi Watanabe, H. Shimada, Makoto Higuchi, Y. Itoh
{"title":"Tau在阿尔茨海默病的四种亚型中积累不同","authors":"T. Yoshizaki, Shinobu Minatani, Hiroto Namba, Akitoshi Takeda, J. Kawabe, Hideko Mizuta, Yasuhiro Wada, A. Mawatari, Yasuyoshi Watanabe, H. Shimada, Makoto Higuchi, Y. Itoh","doi":"10.1111/ncn3.12715","DOIUrl":null,"url":null,"abstract":"Heterogeneity in Alzheimer's disease (AD) has been reported on the basis of clinical, neuropathological, and neuroimaging data. However, most of the indices, including cerebral atrophy evaluated using magnetic resonance imaging and amyloid β (Aβ) accumulation detected using positron emission tomography (PET), lack sensitivity, and specificity for categorization.","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Tau accumulates differently in four subtypes of Alzheimer's disease\",\"authors\":\"T. Yoshizaki, Shinobu Minatani, Hiroto Namba, Akitoshi Takeda, J. Kawabe, Hideko Mizuta, Yasuhiro Wada, A. Mawatari, Yasuyoshi Watanabe, H. Shimada, Makoto Higuchi, Y. Itoh\",\"doi\":\"10.1111/ncn3.12715\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Heterogeneity in Alzheimer's disease (AD) has been reported on the basis of clinical, neuropathological, and neuroimaging data. However, most of the indices, including cerebral atrophy evaluated using magnetic resonance imaging and amyloid β (Aβ) accumulation detected using positron emission tomography (PET), lack sensitivity, and specificity for categorization.\",\"PeriodicalId\":19154,\"journal\":{\"name\":\"Neurology and Clinical Neuroscience\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2023-03-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neurology and Clinical Neuroscience\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/ncn3.12715\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurology and Clinical Neuroscience","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/ncn3.12715","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Tau accumulates differently in four subtypes of Alzheimer's disease
Heterogeneity in Alzheimer's disease (AD) has been reported on the basis of clinical, neuropathological, and neuroimaging data. However, most of the indices, including cerebral atrophy evaluated using magnetic resonance imaging and amyloid β (Aβ) accumulation detected using positron emission tomography (PET), lack sensitivity, and specificity for categorization.
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