巨脊藻根、叶、花乙醇提取物对T47D乳腺癌症细胞系抗癌作用的比较

Alchemy Journal of Chemistry Pub Date : 2018-01-09 DOI:10.18860/AL.V5I1.3690

R. Mutiah, Sukardiman Sukardiman, A. Widyawaruyanti, S. Zulaikah

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引用次数: 11

摘要

本研究旨在研究巨茶卡罗tropis gigantea根、叶、花乙醇提取物的抗癌活性。本实验采用MTT法对乳腺癌细胞系T47D进行实验。结果表明，巨茶甘露根对乳腺癌T47D细胞株的细胞毒性(ic50 89.76 μg/mL)高于叶片(ic50 459.51 μg/mL)和花(ic50 >1000)。基于该结果，根是有效的化疗药物，特别是在乳腺癌。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Comparison of Ethanol Extract from Roots, Leaves, and Flowers of Calotropis gigantea as Anticancer on T47D Breast Cancer Cell Lines

This research aims to find out the anticancer activity of ethanol extract from the roots, leaves, and flowers of Calotropis gigantea . This experiment was conducted by MTT method on T47D breast cancer cell line. The result showed that the root of Calotropis gigantea was more cytotoxic (IC 50 89.76 μg/mL) on T47D breast cancer cell line than the leaves (IC 50 459.51 μg/mL) and the flowers (IC 50 >1000). Based on the result, roots are potent to be chemotherapeutic agent, especially in breast cancer.

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Alchemy Journal of Chemistry

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审稿时长

8 weeks