远程缺血预处理预防造影剂肾病的随机对照研究

Q4 Medicine Open Urology and Nephrology Journal Pub Date : 2019-11-15 DOI:10.2174/1874303x01912010072

K. Sampathkumar, R. Saravanan

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引用次数: 0

摘要

两组在造影剂暴露前均给予静脉生理盐水治疗。主要终点为对比剂诱导的AKI。两组的基线特征具有可比性。两组平均GFR (ml/min)相似(RIPC为54.8+/ 9ml /min;对照54.8+/ 9ml /min)。对照组19/50,IPC组6/50 (p = 0.005)。对照组仅需要血液透析(4/50)(p = 0.058)。对照组30天再住院率(8 /50)高于RIPC组(1/50)(p = 0.01)。RIPC耐受性良好，无不良反应。

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A Randomized Controlled Study of Remote Ischemic Preconditioning for Prevention of Contrast-Induced Nephropathy

Both groups were treated with Intravenous saline therapy before contrast exposure. The primary end point was contrast-Induced AKI. Baseline characteristics were comparable in both groups. Mean GFR in ml/min was similar in both groups (RIPC 54.8+/9 ml/min; Control 54.8+/9 ml/min) . Contrast-induced AKI occurred in 19/50 patients in control group and 6/50 in IPC group (p = 0.005).Hemodialysis was required only in control group (4/50) (p = 0.058). 30 day rehospitalization was more in control group (8 / 50) than RIPC group (1/50) (p = 0.01). RIPC was welltolerated without adverse effects.

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来源期刊

Open Urology and Nephrology Journal Medicine-Urology

CiteScore

0.30

自引率

0.00%

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