S.P. Arevalo Monter , D.I. Hernández Hernández , A.M. Szustkiewicz , A. Zárate , M. Hernández Valencia
{"title":"多囊卵巢综合征患者身体成分的临床表现","authors":"S.P. Arevalo Monter , D.I. Hernández Hernández , A.M. Szustkiewicz , A. Zárate , M. Hernández Valencia","doi":"10.1016/j.rprh.2017.10.017","DOIUrl":null,"url":null,"abstract":"<div><p>Polycystic ovary syndrome it is an endocrine-metabolic dysfunction and it is explained as a female functional hyperandrogenism. Associated to this, several systemic alterations are triggered, with one of these very important dysfunctions being the accumulation of visceral fat tissue. It has been demonstrated that the androgens and the increase of the free fatty acids, as observed in central type obesity, inhibit the hepatic action of insulin that results in compensatory hyperinsulinism secondary to insulin resistance. For this reason, patients with polycystic ovary syndrome present with diverse clinical, hormonal and metabolic characteristics, depending on their body fat and its distribution pattern. The classification into sub-groups can help to identify the systemic dysfunctions that each patient may have. One of these parameters is the phenotype associated with the body composition, which can be measured using the electrical impedance of the body fluids that helps to determine the distribution of the different components of the human body. For this reason, the study of the body composition should be now considered as part of the follow-up of patients with polycystic ovary syndrome, in order to determine the response to the treatments used in the correction of this systemic dysfunction.</p></div>","PeriodicalId":32275,"journal":{"name":"Perinatologia y Reproduccion Humana","volume":"31 2","pages":"Pages 91-95"},"PeriodicalIF":0.0000,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rprh.2017.10.017","citationCount":"0","resultStr":"{\"title\":\"Manifestación clínica de la composición corporal en pacientes con síndrome de ovario poliquístico\",\"authors\":\"S.P. Arevalo Monter , D.I. Hernández Hernández , A.M. Szustkiewicz , A. Zárate , M. Hernández Valencia\",\"doi\":\"10.1016/j.rprh.2017.10.017\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Polycystic ovary syndrome it is an endocrine-metabolic dysfunction and it is explained as a female functional hyperandrogenism. Associated to this, several systemic alterations are triggered, with one of these very important dysfunctions being the accumulation of visceral fat tissue. It has been demonstrated that the androgens and the increase of the free fatty acids, as observed in central type obesity, inhibit the hepatic action of insulin that results in compensatory hyperinsulinism secondary to insulin resistance. For this reason, patients with polycystic ovary syndrome present with diverse clinical, hormonal and metabolic characteristics, depending on their body fat and its distribution pattern. The classification into sub-groups can help to identify the systemic dysfunctions that each patient may have. One of these parameters is the phenotype associated with the body composition, which can be measured using the electrical impedance of the body fluids that helps to determine the distribution of the different components of the human body. For this reason, the study of the body composition should be now considered as part of the follow-up of patients with polycystic ovary syndrome, in order to determine the response to the treatments used in the correction of this systemic dysfunction.</p></div>\",\"PeriodicalId\":32275,\"journal\":{\"name\":\"Perinatologia y Reproduccion Humana\",\"volume\":\"31 2\",\"pages\":\"Pages 91-95\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.rprh.2017.10.017\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Perinatologia y Reproduccion Humana\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0187533717300602\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Perinatologia y Reproduccion Humana","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0187533717300602","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Manifestación clínica de la composición corporal en pacientes con síndrome de ovario poliquístico
Polycystic ovary syndrome it is an endocrine-metabolic dysfunction and it is explained as a female functional hyperandrogenism. Associated to this, several systemic alterations are triggered, with one of these very important dysfunctions being the accumulation of visceral fat tissue. It has been demonstrated that the androgens and the increase of the free fatty acids, as observed in central type obesity, inhibit the hepatic action of insulin that results in compensatory hyperinsulinism secondary to insulin resistance. For this reason, patients with polycystic ovary syndrome present with diverse clinical, hormonal and metabolic characteristics, depending on their body fat and its distribution pattern. The classification into sub-groups can help to identify the systemic dysfunctions that each patient may have. One of these parameters is the phenotype associated with the body composition, which can be measured using the electrical impedance of the body fluids that helps to determine the distribution of the different components of the human body. For this reason, the study of the body composition should be now considered as part of the follow-up of patients with polycystic ovary syndrome, in order to determine the response to the treatments used in the correction of this systemic dysfunction.
期刊介绍:
Perinatología y Reproducción Humana is the official journal of the Instituto Nacional de Perinatología, Mexico. It is aimed at physicians of the area of perinatal and reproductive health (obstetrics and gynecology, maternal and fetal medicine, pediatricians, neonatologists, endocrinologists, infectious disease specialists, and neurologists) and also at health sciences professionals involved in the study of reproduction perinatal and reproductive health (chemists, biologists and neuro-physiologists). It is an electronic biannual journal, that publishes peer-reviewed original articles, in-deep reviews, letters to the editor and special sections related to basic, epidemiological, surgical, and clinical aspects in the area of perinatal and reproductive health, in English or Spanish languages and open access.