展望新的挑战,DKA和新冠肺炎——新冠病毒大流行期间儿科DKA病例回顾谁该怪病毒还是卫生系统?

Vida Tajiknia, Maryam Ghandali, Ardavan Ahmadvand, A. Afrasiabi, Reza Pirdehghan, Mahtab Amoujani, M. Rokni, Roham Azmoudeh
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引用次数: 0

摘要

自新冠疫情爆发的第一个月以来,世界各地的医疗系统都面临着不同的挑战和困难;患有癌症或糖尿病等慢性疾病且免疫系统受损的患者感染和并发症的风险更大。不用说,这个问题在处理糖尿病儿科的儿科临床医生中是极其重要的。糖尿病是儿科患者中最常见的慢性疾病,其最危险和最可怕的并发症是糖尿病酮症酸中毒(DKA)。研究表明,大流行与新发1型糖尿病病例及其致命并发症DKA的增加之间存在密切联系。在这里,我们将查看现有数据,并报告患有这种疾病的病例,试图找到一个大谜题中缺失的部分;新冠肺炎在以前健康的儿童中导致糖尿病的作用是什么?SARS-COV2病毒感染与DKA之间的真正联系是什么?我们将回顾不同的研究,可能的机制,新的t1dm病例和旧的病例,有或没有新冠肺炎感染,DKA病例及其严重程度。
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Looking into a New Challenge, DKA and Covid-19 A Review on Pediatric DKA Cases during New Coronavirus Pandemic Who is to Blame, the Virus or Health System?
Since the first month of this new pandemic situation, all around the world healthcare system has been facing different challenges and difficulties; patients with chronic diseases such as cancer or diabetes with impaired immune system were at greater risk of infections and complications. It goes without saying that this issue was extremely important among pediatric clinicians dealing with diabetic pediatrics. Diabetes is the number one chronic illness among pediatric patients and the most dangerous and frightened complication of it is Diabetic Ketoacidosis (DKA). Studies have shown a strong association between pandemic and increase in new diabetes type 1 cases and its lethal complication called DKA. Here we are going to take a look at existing data and report about cases with this condition trying to find the missing piece of a big puzzle; what is the role of Covid-19 in causing Diabetes in previously healthy kids and what is the real association between SARS-COV2 virus infection and DKA? We are going to review different studies, possible mechanism, new t1dm cases and old cases, with or without covid infection, DKA cases and its severity.
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