考虑医疗资源影响的网络SIR模型的分岔分析与最优控制

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2023-02-22 DOI:10.15388/namc.2023.28.30770
Fang Wang, Maoxing Liu, Lei Zhang, Boli Xie
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引用次数: 0

摘要

提出了一种融合个人医疗资源因素和公共医疗资源因素的基于网络的SIR流行病模型。验证了公共医疗资源因子越大,控制繁殖数越小,个体医疗资源因子越大,可以减弱疾病的传播。我们发现控制繁殖数小于1不足以保证无病平衡点的全局渐近稳定。当医院床位数或个体医疗资源因子足够小时,系统将发生后向分叉。此外,还得到了最优控制和两个时变变量的最优解的存在唯一性。在无标度网络上,不同程度的最优控制水平也不同。最后,通过数值模拟对理论结果进行了验证。本研究表明,保持足够的公共医疗资源和个人医疗资源对于控制传染病至关重要。
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Bifurcation analysis and optimal control of a network-based SIR model with the impact of medical resources
A new network-based SIR epidemic model, which incorporates the individual medical resource factor and public medical resource factor is proposed. It is verified that the larger the public medical resource factor, the smaller the control reproduction number, and the larger individual medical resource factor can weaken the spread of diseases. We found that the control reproduction number below unity is not enough to ensure global asymptotic stability of the disease-free equilibrium. When the number of hospital beds or the individual medical resource factor is small enough, the system will undergoes backward bifurcation. Moreover, the existence and uniqueness of the optimal control and two time-varying variables’s optimal solutions are obtained. On the scale-free network, the level of optimal control is also proved to be different for different degrees. Finally, the theoretical results are illustrated by numerical simulations. This study suggests that maintaining sufficient both public medical resources and individual medical resources is crucial for the control of infectious diseases.
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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