苏托莫医生总医院血液透析患者耐甲氧西林金黄色葡萄球菌(MRSA)携带者的流行情况

Eko Oktiawan Wicaksono, Artaria Tjempakasari, W. Widodo
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摘要

慢性肾脏病(CKD)目前是一种全球性流行病,其发病率在全球范围内呈上升趋势。血液透析是肾功能替代治疗的方法之一。感染是血液透析(HD)患者死亡的第二大原因。耐甲氧西林金黄色葡萄球菌(MRSA)是透析患者细菌血症的常见原因。印度尼西亚CKD耐甲氧西林金黄色葡萄球菌携带者的流行病学数据仍然很少。本研究旨在确定印度尼西亚泗水Soetomo博士学术综合医院肾脏和高血压门诊和血液透析装置患者中MRSA携带者的患病率。研究设计采用描述性分析和横断面研究设计。连续采集样本。研究对象的一般特征数据将使用卡方检验进行分析。本研究包括150名CKD 5期患者,有MRSA携带者的患者人数为6人(4%),其中,接受HD-MRSA携带者的受试者为2人(2.7%),而患有MRSA的非HD患者为4人(5.3%)。耐甲氧西林金黄色葡萄球菌携带者在HD组和非HD组之间没有显著差异(p=0.404)。伴随耐甲氧氯化金黄色葡萄菌携带者的共同因素是糖尿病、高血压、肾结石、痛风和系统性红斑狼疮(SLE)。本研究发现,在CKD非HD或HD的第五阶段组中,MRSA携带者的发病率没有显著差异。MRSA定植存在于CKD的第五阶段患者中,因此对MRSA定置的认识
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Prevalence of Methicillin-resistant Staphylococcus aureus (MRSA) Carrier in Hemodialysis Patients at Dr. Soetomo Academic General Hospital
Chronic kidney disease (CKD) is now a global epidemic, and the prevalence is increasing worldwide. Hemodialysis    is one of the ways to treat by kidney function replacement. Infection is the number two cause of death in patients with hemodialysis (HD). Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of bacteriemia in patients with dialysis. The epidemiological data of MRSA carriers in CKD in Indonesia are still scarce. This study was to determine the prevalence of MRSA carriers in patients at The Kidney and Hypertension Outpatient-clinic and Hemodialysis Installation at Dr. Soetomo Academic General Hospital, Surabaya Indonesia. The study design was descriptive-analytic with a cross- sectional study design. Sampling was collected consecutively. Data on the general characteristics of the research subjects will be analyzed using a Chi-Squared test. There were 150 CKD stage five patients included in this study, the number  of patients has MRSA carrier were 6 (4%), among them, subjects underwent HD MRSA carrier were 2 subjects(2.7%), while for non-HD patients with MRSA were 4 subjects (5.3 %). There were no significant differences in MRSA carriers between HD and non HD groups (p=0.404). Comorbid factors that accompany MRSA carriers are diabetes mellitus, hypertension, kidney stones, gout, and systemic lupus erythematosus (SLE).  This study found, there were no significant differences in the incidence of MRSA carriers in stage five CKD non HD or HD groups. MRSA colonization exists in stage five CKD sufferers, so awareness of MRSA colonization
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