Effect of dialysis duration on serum calcium and phosphorous in hemodialysis patients

Chronic renal insufficiency is associated with changes in mineral and bone metabolism biochemistry and density.2,3 In many countries, physicians follow clinical guidelines for mineral bone disorders to control secondary hyperparathyroidism associated with serum calcium and phosphorous level in patients maintaining hemodialysis (HD).1 With the begin of hemodialysis, histological marks of secondary hyperparathyroidism could be seen in bones of over 50 percent4 of end stage renal disease (ESRD) patients, skeletal defects identified as Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) (the so called as renal osteodystrophy) consist of some types of bone tissue lesions, such as the most widespread high bone turn-over disease but also the a dynamic bone disease.5,6