超重儿童的登革热和疟疾合并感染

Ninny Meutia Pelupessy, Lory Iswanto Latief, Ratna Dewi Artati, Destya Maulani
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摘要

背景:登革热和疟疾是主要在包括印度尼西亚在内的热带国家由蚊子传播的传染病,但只有少数两种疾病在同一地区流行。在登革热流行地区,由于类似的临床症状,疟疾很难诊断。因此,它可能被误诊并影响治疗,从而导致负面结果。病例介绍:本研究报告了一例登革热和疟疾合并感染的病例,该病例发生在一名14岁超重男孩身上,他因发烧、颤抖和严重头痛入院。显微镜检查显示恶性疟原虫的滋养细胞环有几种形式(图1)。实验室检测显示血小板水平较低,为79.000/µL,红细胞比容为43.8%,血清学抗登革热IgM为阴性,抗登革热IgG为阳性。登革热治疗是根据世界卫生组织的登革热诊断指南以及抗疟药物双氢青蒿素哌喹和伯氨喹进行的。在五天的治疗中没有出血或休克,也没有发现严重的疟疾并发症。患者出院后,总体情况有所改善,血液学检查结果正常。结论:本文旨在强调在登革热流行区早期发现和适当管理登革热和疟疾合并感染的重要性,以获得积极的结果并预防并发症。
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Dengue and Malaria Coinfection in An Overweight Child
Background: Dengue and malaria are infectious diseases transmitted by mosquitos mainly in tropical countries, including Indonesia, but there are only a few cases where both diseases are endemic in the same region. Malaria is difficult to diagnose in a dengue-endemic area due to the similar clinical symptoms. As a result, it can be misdiagnosed and affect treatment, resulting in a negative outcome. Case Presentation: This study presented a case of dengue and malaria coinfection in a 14-year-old overweight boy who was admitted to the hospital with fever, shivers, and a severe headache. Microscopic examination showed several form of Plasmodium falciparum’s trophozoite ring (Fig 1). Laboratories test showed a low thrombocyte level, 79.000/µL, hematocrit of 43.8%, serologic anti-dengue IgM was negative, and anti-dengue IgG was positive. Dengue therapy was administered in accordance with the World Health Organization's Dengue Diagnosis Guidelines, as well as the antimalarial drugs dihydroartemisinin-piperaquine and primaquine. There was no bleeding or shock during the five days of treatment, and no severe malaria complications were discovered. The patient was discharged with an improved general condition and normal hematological results. Conclusion: This paper aimed to emphasize the significance of early detection and appropriate management of dengue and malaria co-infection in dengue endemic areas in order to achieve a positive outcome and prevent complications.
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