酶动力学模型中奇异摄动问题的鲁棒数值方法

Q2 Agricultural and Biological Sciences Biomath Pub Date : 2020-09-12 DOI:10.11145/J.BIOMATH.2020.08.227
John J. H. Miller, E. O'Riordan
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引用次数: 2

摘要

研究了酶动力学数学模型中出现的两个耦合非线性初值方程组。系统是奇异摄动的,其中一个组件将包含陡峭的梯度。建立了两个分量的先验参数显式边界。采用一种结合特殊构造的分段均匀网格的数值方法来生成数值逼近,结果表明,与奇异扰动参数的大小无关,该数值逼近点向连续解收敛。数值结果说明了数值方法的计算性能。数值方法的实现也非常简单。
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Robust numerical method for a singularly perturbed problem arising in the modelling of enzyme kinetics
A system of two coupled nonlinear initial value equations, arising in the mathematical modelling of enzyme kinetics, is examined. The system is singularly perturbed and one of the components will contain steep gradients. A priori parameter explicit bounds on the two components are established. A numerical method incorporating a specially constructed piecewise-uniform mesh is used to generate numerical approximations, which are shown to converge pointwise to the continuous solution irrespective of the size of the singular perturbation parameter. Numerical results are presented to illustrate the computational performance of the numerical method. The numerical method is also remarkably simple to implement. 
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来源期刊
Biomath
Biomath Agricultural and Biological Sciences-Agricultural and Biological Sciences (miscellaneous)
CiteScore
2.20
自引率
0.00%
发文量
6
审稿时长
20 weeks
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