流动性数据显示新冠肺炎控制策略在偏远、稀疏和分散人群中的有效性

Frontiers in epidemiology Pub Date : 2023-07-10 eCollection Date: 2023-01-01 DOI:10.3389/fepid.2023.1201810
Yuval Berman, Shannon D Algar, David M Walker, Michael Small
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引用次数: 0

摘要

出于隐私原因,在个人层面从手机收集的数据通常会汇总到人群层面。如果我们有兴趣回答关于均值的问题,或者与由连续体适当建模的小组合作,那么这些数据会立即提供信息。然而,将这种关于群体的数据与需要个人层面信息的模型相结合会增加许多复杂性。如果我们的目标是描述人类的流动性,并通过处理离散的绝对数字来模拟疾病的空间和地理传播,就会出现这种情况。在这项工作中,我们强调了所面临的障碍,并概述了如何克服这些障碍,以有效利用特定的数据集:Google新冠肺炎聚合移动研究数据集(GAMRD)。通过对西澳大利亚州的案例研究,我们首先展示了如何克服这些挑战,从汇总数据中近似交通网络周围的绝对人口流量。西澳大利亚州有许多人口稀少、数据不完整的地区。在这个不断发展的流动网络上覆盖一个包含疫苗接种状态的疾病划分模型,我们进行了模拟,并在不分析数据的情况下得出了关于新冠肺炎在全州传播的有意义的结论。我们可以看到,皮尔巴拉地区的城镇极易受到源自珀斯的疫情的影响。此外,我们表明,对旅行的地区限制不足以阻止病毒传播到西澳大利亚地区。因此,本文中解释的方法可以用于分析类似稀疏人群中的疾病暴发。我们证明,适当使用这些数据可以用来为公共卫生政策提供信息,并对应对疫情产生影响。
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Mobility data shows effectiveness of control strategies for COVID-19 in remote, sparse and diffuse populations.

Data that is collected at the individual-level from mobile phones is typically aggregated to the population-level for privacy reasons. If we are interested in answering questions regarding the mean, or working with groups appropriately modeled by a continuum, then this data is immediately informative. However, coupling such data regarding a population to a model that requires information at the individual-level raises a number of complexities. This is the case if we aim to characterize human mobility and simulate the spatial and geographical spread of a disease by dealing in discrete, absolute numbers. In this work, we highlight the hurdles faced and outline how they can be overcome to effectively leverage the specific dataset: Google COVID-19 Aggregated Mobility Research Dataset (GAMRD). Using a case study of Western Australia, which has many sparsely populated regions with incomplete data, we firstly demonstrate how to overcome these challenges to approximate absolute flow of people around a transport network from the aggregated data. Overlaying this evolving mobility network with a compartmental model for disease that incorporated vaccination status we run simulations and draw meaningful conclusions about the spread of COVID-19 throughout the state without de-anonymizing the data. We can see that towns in the Pilbara region are highly vulnerable to an outbreak originating in Perth. Further, we show that regional restrictions on travel are not enough to stop the spread of the virus from reaching regional Western Australia. The methods explained in this paper can be therefore used to analyze disease outbreaks in similarly sparse populations. We demonstrate that using this data appropriately can be used to inform public health policies and have an impact in pandemic responses.

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