益生菌在对抗COVID-19中的可能作用

Guntur Darmawan, Marshell Tendean, A. Dharmawan, W. William, Henny Tannady Tan, Tamara Atmogo, W. D. Gunardi
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引用次数: 1

摘要

自2019年底首次在武汉报告以来,新冠肺炎感染已在全球蔓延。然而,我们对抗新冠肺炎的斗争仍然受到治疗方式的限制,但这给研究人员探索有前景的治疗候选药物带来了巨大挑战。基于先前对益生菌在免疫系统和呼吸道感染中的作用的研究,益生菌似乎是潜在的候选者。益生菌通过肠道和肺部之间的连接以一种独特的方式发挥作用,因为两者都表达血管紧张素转换酶2(ACE2),其中ACE2与新冠肺炎高度结合。目前,没有任何指南正式将益生菌作为新冠肺炎治疗的一部分。因此,本研究旨在回顾益生菌与免疫系统的联系及其作为新冠肺炎治疗一部分的潜在作用。
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The Possible Role of Probiotics in Combating COVID-19
Since first reported in Wuhan in the end of 2019, COVID-19 infection has spread globally. However, our battle against COVID-19 is still limited with treatment modalities, yet giving a big challenge for researchers to explore promising treatment candidate. Probiotics, based on previous studies of its role in immune system and respiratory tract infection, seem to be potential candidate. Probiotics work in a distinct way through connectivity between gut and the lung, since both have expression of angiotensin converting enzyme2 (ACE2) of which highly bound by COVID-19. At present, no guidelines formally include probiotics as part of COVID-19 treatment. Hence, this study aimed to review the link of probiotics and immune system and its potential role as part of COVID-19 treatment.
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