生物库是现代转化肿瘤学研究的重要工具

Q3 Agricultural and Biological Sciences Biological Communications Pub Date : 2022-12-31 DOI:10.21638/spbu03.2022.405
Elena Petersen, Darya Chudakova, E. Shabalina, A. Shiryaev, N. Sukortseva, G. Zhemerikin, P. Karalkin, I. Reshetov
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引用次数: 0

摘要

生物银行的创建和使用是一个积极发展的领域,在生物技术和生物医学的许多分支的发展中起着重要作用,包括肿瘤学和转化医学。在这篇综述中,基于对80多篇俄罗斯和国外出版物的分析,我们描述了生物银行的现状及其未来前景。讨论了生物银行的多样性及其产生的问题,包括对不同类型研究的适用性限制以及发展前景。强调了生物库在研究恶性肿瘤,包括罕见病/孤儿病,以及在发展新的诊断和治疗方法、个性化医疗和临床前筛选研究方面的作用。
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Biobanks as an important tool in modern translational oncology
The creation and use of biobanks is an actively growing field that plays an important role in the development of many branches of biotechnology and biomedicine, including oncology and translational medicine. In this review, based on the analysis of more than 80 Russian and foreign publications, we describe the current state of biobanking and its future perspectives. The diversity of biobanking and the problems arising from it, including the limits of applicability to different types of research, as well as the prospects for development are discussed. The role of biobanks in the study of malignant neoplasms, including rare/orphan diseases, and in the development of new diagnostic and therapeutic approaches, personalised medicine and pre-clinical screening studies, are highlighted.
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来源期刊
Biological Communications
Biological Communications Agricultural and Biological Sciences-Agricultural and Biological Sciences (all)
CiteScore
1.70
自引率
0.00%
发文量
21
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