南非约翰内斯堡医院门诊病人幽门螺杆菌感染率

Osuji Emmanuel Chinaka
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摘要

背景:幽门螺旋杆菌常与胃脘不适和胃癌有关。目的:了解门诊病人幽门螺杆菌感染的流行情况。方法:研究招募了200名年龄在10-50岁之间的门诊患者,并对其进行了幽门螺杆菌感染筛查。获得了约翰内斯堡4家不同医院伦理委员会的伦理批准以及参与者的知情同意。血液和粪便样本以及鼻孔的呼吸样本被用于调查。血清学、培养和尿素呼吸试验分别用于血液、粪便和排出物的评估。对所得值进行统计学分析。结果:74例(37%)患者幽门螺杆菌检测呈阳性。阳性病例男性占47%,女性占53%。66%的黑人检测呈阳性,而白人为34%。检测呈阳性的酒精和香烟消费者分别为29人(39%)和26人(35%)。如厕后洗手率为10(14%),饭前洗手率为9(12%)。结论:研究结果表明,年龄、性别、种族和食用某些食物物质可能易导致幽门螺杆菌感染。
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The Prevalence of Helicobacter Pylori Infection among Outpatients Attending Hospitals in Johannesburg South Africa
Background: H. pylori is commonly incriminated in most cases of epigastric discomfort and stomach cancer. Aim: The study determined the prevalence of H. pylori infection among patients visiting out patient’s clinic. Methodology: Two hundred patients with age range 10-50 years attending clinics were recruited for the study and screened for H. Pylori infection. Ethical approval was obtained from the Ethics Committee of 4 different hospitals in Johannesburg as well as informed consent of the participants. Blood and Stool samples and breath from the Nostril were used for the investigation. Serological, Cultural and Urea Breath Test were methods used for assessment of the Blood, Stool and Expels respectively. Values obtained were statistically analyzed. Results: Seventy four (37%) patients tested positive to H. Pylori. Males had 47% positive cases while female were 53%. 66% of the black race tested positive while the white were 34%. Alcohol and Cigarette Consumers who tested positive were 29 (39%) and 26(35%) respectively. Hand washing after visiting toilet is 10(14%) and hand washing before meal is 9 (12%). Conclusion: The findings of this study showed that age, sex, race and some food substances consuming may predispose to H. prlori infection.
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