儿童急性肾损伤是丙烯菊酯中毒(“全力以赴”)的罕见并发症

Anjana Ks, Raghunath Cn, C. Arvind
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引用次数: 1

摘要

拟除虫菊酯类药物因其对人体和药物局部治疗疥疮和头虱的高效低毒性而被广泛用作商业和家用杀虫剂。丙菊酯是天然存在的拟除虫菊酯的结构衍生物,也是液体驱蚊剂中的活性成分。接触或摄入拟除虫菊酯类药物引起的急性人类中毒是罕见的,因为其皮肤吸收不良,代谢迅速,组织积累很少。在这里,我们报告了一例五岁儿童的意外氯氰菊酯中毒(“ALL–OUT”,一种液体驱蚊剂),该儿童有吸入性肺炎引起的低血容量性休克等直接并发症和急性肾损伤等延迟并发症,肝酶升高,需要肾替代治疗,并顺利康复。
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Acute Kidney Injury as a Rare Complication of Prallethrin Poisoning (“All-Out”) in a Child
Pyrethroids are widely used as commercial and domestic insecticides due to their high effectiveness and low toxicity in humans and in medicine for the topical treatment of scabies and head lice. Prallethrin is a structural derivative of naturally occurring pyrethrin and active ingredient in liquid mosquito repellents. Acute human poisoning from exposure or ingestion of pyrethroids is rare because of poor dermal absorption and rapid metabolism with little tissue accumulation. Here we present a case of accidental Prallethrin poisoning(“ALL –OUT”, a liquid mosquito repellent) in a five year old child who had immediate complication as hypovolemic shock with aspiration pneumonia and delayed complications like acute kidney injury, with elevated liver enzymes, requiring renal replacement therapy and had an uneventful recovery.
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