W. Salleh, S. Khamis, M. Nadri, Hakimi Kassim, A. Tawang
{"title":"Cyathocalyx pruniferus（Maingay ex Hook.f.&Thomson）精油的化学成分和乙酰胆碱酯酶抑制作用J.Sinclair","authors":"W. Salleh, S. Khamis, M. Nadri, Hakimi Kassim, A. Tawang","doi":"10.37929/nveo.770303","DOIUrl":null,"url":null,"abstract":"The chemical composition and acetylcholinesterase inhibitory activity of the essential oil from the leaf of Cyathocalyx pruniferus growing in Pahang, Malaysia was investigated for the first time. The essential oil was obtained by hydrodistillation and fully characterized by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of thirty chemical components (95.53%) were successfully identified in the essential oil which was characterized by high proportions of α-pinene (25.40%), germacrene D (20.20%), β-caryophyllene (10.78%), and δ-cadinene (6.44%). Acetylcholinesterase inhibitory activity was evaluated against the Ellman method, and the essential oil showed good inhibition against acetylcholinesterase (I: 75.5%) assay. To the best of our knowledge, this is the first study of the composition of the essential oil report concerning the genus Cyathocalyx.","PeriodicalId":36935,"journal":{"name":"Natural Volatiles and Essential Oils","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Chemical composition and acetylcholinesterase inhibition of the essential oil of Cyathocalyx pruniferus (Maingay ex Hook.f. & Thomson) J.Sinclair\",\"authors\":\"W. Salleh, S. Khamis, M. Nadri, Hakimi Kassim, A. Tawang\",\"doi\":\"10.37929/nveo.770303\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The chemical composition and acetylcholinesterase inhibitory activity of the essential oil from the leaf of Cyathocalyx pruniferus growing in Pahang, Malaysia was investigated for the first time. The essential oil was obtained by hydrodistillation and fully characterized by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of thirty chemical components (95.53%) were successfully identified in the essential oil which was characterized by high proportions of α-pinene (25.40%), germacrene D (20.20%), β-caryophyllene (10.78%), and δ-cadinene (6.44%). Acetylcholinesterase inhibitory activity was evaluated against the Ellman method, and the essential oil showed good inhibition against acetylcholinesterase (I: 75.5%) assay. To the best of our knowledge, this is the first study of the composition of the essential oil report concerning the genus Cyathocalyx.\",\"PeriodicalId\":36935,\"journal\":{\"name\":\"Natural Volatiles and Essential Oils\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-11-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Natural Volatiles and Essential Oils\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37929/nveo.770303\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Volatiles and Essential Oils","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37929/nveo.770303","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
Chemical composition and acetylcholinesterase inhibition of the essential oil of Cyathocalyx pruniferus (Maingay ex Hook.f. & Thomson) J.Sinclair
The chemical composition and acetylcholinesterase inhibitory activity of the essential oil from the leaf of Cyathocalyx pruniferus growing in Pahang, Malaysia was investigated for the first time. The essential oil was obtained by hydrodistillation and fully characterized by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of thirty chemical components (95.53%) were successfully identified in the essential oil which was characterized by high proportions of α-pinene (25.40%), germacrene D (20.20%), β-caryophyllene (10.78%), and δ-cadinene (6.44%). Acetylcholinesterase inhibitory activity was evaluated against the Ellman method, and the essential oil showed good inhibition against acetylcholinesterase (I: 75.5%) assay. To the best of our knowledge, this is the first study of the composition of the essential oil report concerning the genus Cyathocalyx.
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