Wei Zhang, Fei Liu, Lixing Wang, D. Guo, Xin Xu, Bin Chen, Jun‐hao Jiang, Jue Yang, Zhenyu Shi, W. Fu
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The median of tumor size, procedural blood loss, procedural time, and length of hospital stay was 3.0 (1.2-5.5) cm, 200 (0-2 500) ml, 162 (85-430) min, and 10 (6-28) d, respectively. Seventy-two patients had carotid vascular intervention during the procedure, and thirty-three patients had neurological complications after the procedure. Correlation analysis showed that the tumor size had positive relationship with blood loss (Spearman R=0.35, P<0.01) and procedural time (Spearman R= 0.54, P<0.01). Tumor size was positively associated with the risk of cranial neurological complication (OR=1.72, 95% CI 1.08-2.73, P=0.02) and carotid vascular intervention (OR=2.69, 95% CI 1.27-5.69, P=0.01). There were four patients who were diagnosed with malignant CBT due to the metastasis. Three suffered CBT recurrence after 1, 5, and 7 years during the follow up. \n \n \nConclusions \nShamblin Ⅱ or Ⅲ CBTs should be intervened as early as possible to facilitate the surgical resection, as well as to reduce the risk of carotid vascular and neurological complications. \n \n \nKey words: \nCarotid body tumor; Vascular surgical procedures; Postoperative complications","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Long-term follow up outcomes of surgical resection of Shamblin II/III carotid body tumor: a single center analysis\",\"authors\":\"Wei Zhang, Fei Liu, Lixing Wang, D. Guo, Xin Xu, Bin Chen, Jun‐hao Jiang, Jue Yang, Zhenyu Shi, W. 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引用次数: 0
摘要
目的探讨ShamblinⅡ/Ⅲ颈动脉体瘤(CBT)的肿瘤大小与手术疗效及预后的关系。方法回顾性分析2011年4月至2017年12月行ShamblinⅡ和ⅢCBTs肿瘤切除术的88例患者。并对手术切除的远期预后进行评价。结果1例患者术后多脏器功能衰竭死亡,2例患者放弃手术。围手术期死亡率为1%。本文对85例87个病灶成功切除的病例进行了分析。有13例ShamblinⅡ和74例ShamblinⅢct切除术。2例患者行双侧cbt切除术。肿瘤大小、手术出血量、手术时间和住院时间的中位数分别为3.0 (1.2-5.5)cm、200 (0-2 500)ml、162 (85-430)min和10 (6-28)d。72例患者在手术过程中有颈动脉血管介入,33例患者术后有神经系统并发症。相关分析显示,肿瘤大小与出血量(Spearman R=0.35, P<0.01)和手术时间(Spearman R= 0.54, P<0.01)呈正相关。肿瘤大小与颅神经系统并发症(OR=1.72, 95% CI 1.08-2.73, P=0.02)和颈动脉血管干预(OR=2.69, 95% CI 1.27-5.69, P=0.01)呈正相关。有4例患者因转移而被诊断为恶性CBT。3名患者随访1年、5年和7年后出现CBT复发。结论应尽早干预ShamblinⅡ或Ⅲcbt,以方便手术切除,减少颈动脉血管和神经系统并发症的发生。关键词:颈动脉体瘤;血管外科手术;术后并发症
Long-term follow up outcomes of surgical resection of Shamblin II/III carotid body tumor: a single center analysis
Objective
To evaluate the correlation between tumor size and surgical outcomes of Shamblin Ⅱ/Ⅲ carotid body tumor (CBT) and the prognosis.
Methods
From Apr 2011 to Dec 2017, 88 patients with Shamblin Ⅱ and Ⅲ CBTs undergoing tumor resection were retrospectively analyzed. The long-term prognosis of surgical resection was also evaluated.
Results
One patient died of multi-organ failure postoperatively, two patients abandoned surgery. The perioperative mortality was 1%. 85 patients having 87 lesions successfully resected were analyzed. There were 13 Shamblin Ⅱ and 74 Shamblin Ⅲ CBTs resection. Two patients had bilateral CBTs resection. The median of tumor size, procedural blood loss, procedural time, and length of hospital stay was 3.0 (1.2-5.5) cm, 200 (0-2 500) ml, 162 (85-430) min, and 10 (6-28) d, respectively. Seventy-two patients had carotid vascular intervention during the procedure, and thirty-three patients had neurological complications after the procedure. Correlation analysis showed that the tumor size had positive relationship with blood loss (Spearman R=0.35, P<0.01) and procedural time (Spearman R= 0.54, P<0.01). Tumor size was positively associated with the risk of cranial neurological complication (OR=1.72, 95% CI 1.08-2.73, P=0.02) and carotid vascular intervention (OR=2.69, 95% CI 1.27-5.69, P=0.01). There were four patients who were diagnosed with malignant CBT due to the metastasis. Three suffered CBT recurrence after 1, 5, and 7 years during the follow up.
Conclusions
Shamblin Ⅱ or Ⅲ CBTs should be intervened as early as possible to facilitate the surgical resection, as well as to reduce the risk of carotid vascular and neurological complications.
Key words:
Carotid body tumor; Vascular surgical procedures; Postoperative complications