具有显性和隐性行为变化的新冠肺炎大流行的数学建模、分析和模拟

Comfort Ohajunwa, Kirthi Kumar, P. Seshaiyer
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引用次数: 7

摘要

随着COVID-19病例在全球范围内持续上升,许多研究人员开发了数学模型来帮助捕捉COVID-19的传播动态。具体来说,分区SEIR模型及其变体已被广泛应用。这些模型在包括的隔间类型、传播率的性质、季节性和其他几个因素方面有所不同。然而,尽管COVID-19的传播在很大程度上归因于人群中广泛的社会行为,但其中一些SEIR模型并未考虑到这些行为。在这个项目中,我们考虑了包含各种行为的基于seir的新型模型。我们创建了一个基线模型,并探索将显性和隐性行为变化结合起来。此外,使用下一代矩阵方法,我们得到了一个基本的繁殖数,它表示单个感染个体的估计继发病例数。对我们制作的各种模型进行了数值模拟,并创建了用户友好的图形用户界面。在未来,我们计划扩展我们的项目,以考虑口罩的使用,基于年龄的行为和传播率,以及混合模式。
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Mathematical modeling, analysis, and simulation of the COVID-19 pandemic with explicit and implicit behavioral changes
Abstract As COVID-19 cases continue to rise globally, many researchers have developed mathematical models to help capture the dynamics of the spread of COVID-19. Specifically, the compartmental SEIR model and its variations have been widely employed. These models differ in the type of compartments included, nature of the transmission rates, seasonality, and several other factors. Yet, while the spread of COVID-19 is largely attributed to a wide range of social behaviors in the population, several of these SEIR models do not account for such behaviors. In this project, we consider novel SEIR-based models that incorporate various behaviors. We created a baseline model and explored incorporating both explicit and implicit behavioral changes. Furthermore, using the Next Generation Matrix method, we derive a basic reproduction number, which indicates the estimated number of secondary cases by a single infected individual. Numerical simulations for the various models we made were performed and user-friendly graphical user interfaces were created. In the future, we plan to expand our project to account for the use of face masks, age-based behaviors and transmission rates, and mixing patterns.
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来源期刊
Computational and Mathematical Biophysics
Computational and Mathematical Biophysics Mathematics-Mathematical Physics
CiteScore
2.50
自引率
0.00%
发文量
8
审稿时长
30 weeks
期刊最新文献
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