支气管热成形术后肺气病1例

Steger M, Migueres N, Khayath N, Marcot C, Matau C, Arboit F, Ohana M, De Blay F
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引用次数: 1

摘要

支气管热成形术(BT)是一种支气管镜下治疗的严重哮喘患者,尽管最佳的药物治疗仍然无法控制。一些不良反应和急性放射学异常已被描述,但挖掘性肺病从未被报道为BT的并发症。我们描述了在最后一次BT手术后挖掘性肺病的发展。一名60岁的妇女患有严重的不受控制的哮喘,尽管进行了最大的药物治疗,但她接受了BT。在第三次手术后,在全身皮质类固醇治疗减少后,她的哮喘恶化并伴有呼吸恶化。胸部计算机断层扫描显示结节状挖掘性混浊与支气管树接触,局限于上叶和舌。本病例提示,对支气管黏膜的强烈热刺激可导致组织脆性和肺泡性肺病变
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A Case of Excavated Pneumopathy after Bronchial Thermoplasty
Bronchial thermoplasty (BT) is a bronchoscopic treatment for patients with severe asthma that remains uncontrolled despite optimal medical therapy. Several adverse effects and acute radiological abnormalities have been described, but excavated pneumopathy has never been reported as a complication of BT. We describe the development of excavated pneumopathy after the last BT procedure. A 60-year-old woman with severe uncontrolled asthma, despite maximal medical treatment, underwent BT. After the third procedure, she developed an exacerbation of asthma with respiratory deterioration after a reduction in systemic corticosteroid treatment. Chest computer tomography revealed nodular excavated opacities in contact with the bronchial tree, limited to the upper lobes and the lingula. This case suggested that intense thermal stimulation of the bronchial mucosa may lead to tissue fragility and alveolar lung lesions
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