ART周期中卵泡液和血清抗苗勒管激素水平与妊娠率的关系

Perinatologia y Reproduccion Humana Pub Date : 2018-03-01 DOI:10.1016/j.rprh.2018.03.001

M. Zargar , M. Najafian , Z. Zamanpour

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引用次数: 2

摘要

目的测定血清和卵泡液中抗苗勒管激素水平、含量及其与辅助生殖技术成功率的关系。方法对50例接受ART周期治疗的不孕症患者，于取卵当天测定卵泡液及血清抗苗勒管激素水平。然后将患者分为可育组和非可育组。结果妊娠试验结果阳性13例，阴性37例。血清和卵泡液抗苗勒管激素水平第一组高于第二组(P <0.05)。第一组和第二组患者卵泡液抗苗勒管激素平均水平分别为5.12和4.23。第一组和第二组血清抗苗勒管激素水平分别为1.76和1.49。结论血清和卵泡液中抗苗勒管激素水平升高与ART周期成功率和卵母细胞质量显著正相关;因此，抗苗勒管激素可以作为抗逆转录病毒治疗成功周期的积极预测因子。

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Relationship between follicular fluid and serum anti-Mullerian hormone levels and pregnancy rate in ART cycles

Objective

This study is aimed at determining the serum and follicular fluid level of anti-Mullerian hormone, its quality, and relationship between anti-Mullerian hormone level with assisted reproductive technology (ART) success rates.

Method

In 50 infertile patients who underwent the ART cycle, follicular fluid and serum levels of anti-Mullerian hormone were measured on oocyte retrieval day. Patients were then divided into two groups of fertile and non-fertile.

Results

Pregnancy test result was positive in 13 and negative in 37 patients. Serum and follicular fluid level of anti-Mullerian hormone was higher among the first group than the second group (P < 0.05). Mean follicular fluid level of anti-Mullerian hormone was 5.12 and 4.23 among the first and second groups, respectively. Mean serum anti-Mullerian hormone level was 1.76 in the first group and 1.49 in the second group.

Conclusions

Higher level of anti-Mullerian hormone in serum and follicular fluid has a significantly positive correlation with the success rate in ART cycles and oocyte quality; therefore, anti-Mullerian hormone can be a positive predictor of ART success cycles.

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来源期刊

Perinatologia y Reproduccion Humana

自引率

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审稿时长

20 weeks

期刊介绍： Perinatología y Reproducción Humana is the official journal of the Instituto Nacional de Perinatología, Mexico. It is aimed at physicians of the area of perinatal and reproductive health (obstetrics and gynecology, maternal and fetal medicine, pediatricians, neonatologists, endocrinologists, infectious disease specialists, and neurologists) and also at health sciences professionals involved in the study of reproduction perinatal and reproductive health (chemists, biologists and neuro-physiologists). It is an electronic biannual journal, that publishes peer-reviewed original articles, in-deep reviews, letters to the editor and special sections related to basic, epidemiological, surgical, and clinical aspects in the area of perinatal and reproductive health, in English or Spanish languages and open access.