Yanyan Lin, Jun Yan, Qi-Yong Zhang, Xiaoliang Zhu, Xun Li
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Safety and effectiveness of ERCP for patients with decompensated cirrhosis combined with choledocholithiasis
Objective
To evaluate safety and effectiveness of endoscopic retrograde cholangiopancreatography (ERCP) for patients with decompensated cirrhosis combined with choledocholithiasis.
Methods
A retrospective analysis was performed on data of 79 patients with decompensated cirrhosis combined with choledocholithiasis, 92 patients with chronic viral hepatitis, and 114 patients without liver disease who underwent ERCP at the First Hospital of Lanzhou University from December 2012 to December 2016. Intraoperative operating conditions, postoperative improvement of liver function indices, and complications among the three groups were compared and analyzed.
Results
The level of serum prothrombin time before ERCP in patients with cirrhosis (12.9±2.2) s was higher than that in patients with chronic viral hepatitis (12.1±1.9) s and those without liver disease (11.7±1.4) s, the difference was statistically significant (F=21.530, P 0.05) .
Conclusion
ERCP is safe and effective for Child-Pugh A and B patients with decompensated cirrhosis combined with choledocholithiasis. Liver function and blood coagulation function should be improved in Child-Pugh C patients before ERCP.
Key words:
Choledocholithiasis; Liver cirrhosis; Hepatitis, viral; Cholangiopancreatography, endoscopic retrograde
期刊介绍：
Chinese Journal of Digestive Endoscopy is a high-level medical academic journal specializing in digestive endoscopy, which was renamed Chinese Journal of Digestive Endoscopy in August 1996 from Endoscopy.
Chinese Journal of Digestive Endoscopy mainly reports the leading scientific research results of esophagoscopy, gastroscopy, duodenoscopy, choledochoscopy, laparoscopy, colorectoscopy, small enteroscopy, sigmoidoscopy, etc. and the progress of their equipments and technologies at home and abroad, as well as the clinical diagnosis and treatment experience.
The main columns are: treatises, abstracts of treatises, clinical reports, technical exchanges, special case reports and endoscopic complications.
The target readers are digestive system diseases and digestive endoscopy workers who are engaged in medical treatment, teaching and scientific research.
Chinese Journal of Digestive Endoscopy has been indexed by ISTIC, PKU, CSAD, WPRIM.
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