角膜塑形术与青少年近视的视觉运动训练

IF 2.9 4区 医学 Q1 Medicine Journal of biomedical nanotechnology Pub Date : 2023-08-01 DOI:10.1166/jbn.2023.3651
Yao Chen, Jingjing Zhang, Hui Huang, Bo Su
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引用次数: 0

摘要

本研究旨在探讨角膜塑形术(orthokeratology, Ortho-K)联合视觉运动训练在青少年近视治疗中的作用。我们纳入156例近视患者,随机分为(视觉运动训练+Ortho-K)联合组和(仅)Ortho-K组。比较各组治疗前后角膜形态变化(水平角度数[HK]、垂直角度数[VK]、角膜中央厚度[CCT]、角膜内皮细胞密度)、调节功能(正、负相对调节[PRA、NRA]、调节幅度、调节灵敏度)、眼轴、视力(裸眼视力、屈光度)、泪膜稳定性(BUT试验和SIT试验)、眼压、安全性。此外,我们对初始年龄和屈光度对轴向生长的影响进行了Spearman相关分析。治疗后,两组患者角膜HK、VK、CCT水平均显著降低,内皮细胞密度无明显变化。联合用药组PRA、调节幅度、调节灵敏度均有较高的改善,可延缓眼轴生长,改善裸眼视力和屈光度。同时,患者的初始年龄与轴向生长呈显著负相关。此外,联合组在佩戴Ortho-K后的BUT和SIT恢复相对较好。综上所述,Ortho-K联合视觉运动训练能更好地矫正青少年近视患者的视力,延缓眼轴生长。此外,干预越早,效果越好。
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Orthokeratology and Visual Motor Training for Juvenile Myopia
This study aimed to explore the effect of orthokeratology (Ortho-K) combined with visual motor training in juvenile myopia. We included 156 myopia patients, which were randomly divided into the combined (visual motor training+Ortho-K) and Ortho-K (only) groups. Corneal morphological changes (horizontal keratometry [HK], vertical keratometry [VK], central corneal thickness [CCT], and corneal endothelial cell density), regulatory function (positive and negative relative accommodation [PRA, NRA], regulatory amplitude, and regulatory sensitivity), ocular axis, visual acuity (naked visual acuity, Diopter), tear film stability (BUT test and SIT test), intraocular pressure, and safety before and after treatment were compared between groups. Moreover, we performed a Spearman correlation analysis on the effects of initial age and diopter on axial growth. After treatment, HK, VK of cornea, and CCT levels significantly decreased in both groups while no significant changes were found in endothelial cell density. In the combined group, there was a higher improvement in PRA, accommodation amplitude, and accommodation sensitivity, which could delay ocular axis growth and improve naked eye vision and diopters. Meanwhile, a significant negative correlation was found between patients’ initial age and axial growth. Moreover, BUT and SIT recovery in the combined group were relatively better after wearing Ortho-K. In conclusion, Ortho-K combined with visual motor training could better correct the vision of juvenile myopia patients and delay ocular axis growth. In addition, the earlier the intervention, the better the effect.
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来源期刊
CiteScore
4.30
自引率
17.20%
发文量
145
审稿时长
2.3 months
期刊介绍: Information not localized
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