Green synthesis of silver nanoparticles from Aspergillus flavus and their antibacterial performance

Abstract Many methods have been developed for the synthesis of silver nanoparticles (Ag-NPs), yet disadvantages are there to declined their catalytic activity due to the large size with small surface area. Hence, herein, the fungus mediated synthesis of Ag-NPs has been reported. The synthesized Ag-NPs were further characterized by XRD, SEM, EDS, and UV–Vis spectroscopy to study the particle size, surface, crystalline nature, phase formation of Ag-NPs and the produced particles were found to be 41.9 nm. The antibacterial efficiency of synthesized Ag-NPs was examined on various bacteria including Streptococcus pyrogenes, Staphylococcus aureus, Bacillus coagulans, Klebsiella pneumoniae and Corynibacterium glutamicum. The Ag-NPs could be considered as excellent broad-spectrum antibacterial agent. More prominently, the Ag-NPs produced by Aspergillus flavus exhibited potent antibacterial activity against certain pathogens. Bacillus coagulans exhibited maximum zone of inhibition 25.16 ± 0.80 at 80 μg/mL with respective to the standard antibiotic 26.66 ± 1.22 at 30 μg/mL concentration.