类胡萝卜素-健康美丽皮肤的有效自由基清除剂

Anja Elpelt, S. B. Lohan, M. Darvin, J. Lademann, M. Meinke
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引用次数: 0

摘要

这种状态被称为氧化应激。自由基攻击体内的生物分子,如蛋白质、脂质或DNA,导致损伤、功能减少甚至丧失。这可能导致各种疾病的发展,如神经退行性疾病[2]、心血管疾病[3]以及包括皮肤癌症在内的皮肤疾病[4]。氧化应激还导致某些信号通路的激活,从而使皮肤深层的弹性胶原纤维降解,仅少量产生,这导致了皮肤衰老的典型特征[5]。我们的饮食在多大程度上有助于以自然和可控的方式预防氧化应激,从而预防疾病和皮肤衰老?为了回答这个问题,这篇小综述更详细地阐述了基于抗氧化剂的膳食补充剂,特别是类胡萝卜素,在保持健康和年轻外表方面的潜力。摘要自由基与各种疾病和皮肤衰老有关。为了减少和预防这种风险,我们的身体会产生能够中和自由基的抗氧化剂。然而,食物中需要摄入一些抗氧化剂,因此均衡多样的饮食以及充足的运动对人类健康和美丽至关重要。蔬菜,尤其是卷曲的羽衣甘蓝,由于类胡萝卜素的存在,显示出非常好的抗氧化能力。由于通常不食用推荐的每日蔬菜摄入量,因此膳食补充剂很有可能以可控和自然的方式摄入类胡萝卜素。基于类胡萝卜素的膳食补充剂对皮肤的积极作用已经在几项针对健康志愿者的研究中得到了证明。创新的非侵入性测量方法表明,蔬菜油提取物不仅能显著减少皮肤中的自由基,还能显著减少与年龄相关的胶原蛋白分解,并对皱纹体积等皮肤参数产生积极影响。因此,不同天然类胡萝卜素的平衡混合物有助于保持健康和美丽。
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Carotenoids-Effective Radical Scavengers for Healthy and Beautiful Skin
state of which is called oxidative stress. Free radicals attack the biomolecules in the body, such as proteins, lipids or DNA, inducing damage and reduction or even loss of function. This can contribute to the development of various diseases, such as neurodegenerative [2], cardiovascular [3] as well as skin diseases including skin cancer [4]. Oxidative stress also leads to the activation of certain signaling pathways, whereby the elastic collagen fibers in the deeper layers of the skin are degraded and only produced in small amounts, which leads to the typical characteristics of skin aging [5]. To what extent can our diet help to prevent oxidative stress and thus diseases and skin aging in a natural and controlled way? To answer this question, this mini review address in more detail the potential of antioxi-dant-based dietary supplements, especially carotenoids, to maintain health and youthful appearance. Abstract Free radicals are involved in various diseases and skin aging. To reduce and prevent this risk, our body produces antioxidants that can neutralize free radicals. However, some antioxidants need to be taken up with food, so a balanced and varied diet is essential for human health and beauty, along with sufficient exercise. Vegetables, especially curly kale, show very good antioxidative capacity due to the presence of carotenoids. As the recommended daily intake of vegetables is usually not consumed, dietary supplements are a good possibility to ingest carotenoids in a controlled and natural way. The positive effect of carotenoid-based dietary supplements on the skin has already been shown in several studies on healthy volunteers. Innovative non-invasive measuring methods have shown that oil extracts from vegetables significantly reduce not only free radicals in the skin but also the age-related breakdown of collagen and have a positive effect on skin parameters such as wrinkle volume. Thus, a balanced mixture of different natural carotenoids contributes to maintaining health and beauty.
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