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Effects of a Short-Term Telework Program in a Local City with BusinessT ravel on Stress Indicators among Workers in a Japanese MetropolitanA rea: A Preliminary Study 短期远程办公计划对日本大都市员工压力指标的影响:初步研究
Pub Date : 2022-01-01 DOI: 10.31488/heph.171
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引用次数: 0
Impact of a Pluridisciplinary Protocol of Respiratory Physiotherapy and Active Music Therapy on Anxiety, Depression and Pain on Lung Post-Transplant Patients (PPRPAM) 多学科呼吸物理治疗和积极音乐治疗对肺移植术后患者焦虑、抑郁和疼痛的影响
Pub Date : 2022-01-01 DOI: 10.31488/heph.175
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引用次数: 0
Longitudinal Change in The Cumulative Incidence and Maintenance Rate of Metabolic Syndrome among Participants of the Specifific Health Check and Guidance System in Japan 日本特定健康检查与指导系统参与者代谢综合征累积发病率和维持率的纵向变化
Pub Date : 2022-01-01 DOI: 10.31488/heph.177
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引用次数: 0
Opportunities to Enhance Dental Education through Partnerships with Communities in Need 透过与有需要社区合作,加强牙科教育的机会
Pub Date : 2022-01-01 DOI: 10.31488/heph.173
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引用次数: 0
Proposal of Need Care Indicators for the Male Elderly People -An Approach Based on Phase Angle 男性老年人需求护理指标的提出——基于相位角的方法
Pub Date : 2022-01-01 DOI: 10.31488/heph.172
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引用次数: 0
Virtual Horticultural Therapy: A Qualitative Study Capturing University Students’ Perspectives on Benefifits, Challenges and Future Issues 虚拟园艺疗法:一项捕捉大学生对益处、挑战和未来问题观点的定性研究
Pub Date : 2022-01-01 DOI: 10.31488/heph.176
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引用次数: 0
Three Arm Pilot Study with Waiting Group Control to Quantify the Effect of Information Field Analysis and Vibration and the Application of Individualized Microcurrent Treatments on Improvement of General Wellbeing and Goal Attainment in Healthy Volunteers 信息场分析、振动及个体化微电流治疗在改善健康志愿者总体幸福感和目标实现方面的应用的三臂试验性研究
Pub Date : 2022-01-01 DOI: 10.31488/heph.174
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引用次数: 0
Distal Sensory Peripheral Neuropathy: An Undervalued Determinant of Wellbeing. 远端感觉周围神经病变:一个被低估的健康决定因素。
Pub Date : 2021-10-01 DOI: 10.31488/heph.169
J. Anastasi, Daniel K. Devine, B. Capili
Peripheral neuropathy (PN) is a significant, frequently debilitating complication of HIV infection and diabetes caused by damage to the sensory and motor peripheral nerves. In persons with HIV infection (PWH), neuropathy is thought to result from highly active antiretroviral therapy (HAART) neurotoxicity, particularly stavudine (d4T), dideoxycytidine (ddC), and didanosine (ddI), effects of HIV, or both [1]. Advanced age, taller height (as a proxy for longer neuronal axons), comorbid diabetes, and treatment with nucleotide reverse transcriptase inhibitors (NRTI), increased PN risk [2]. Among patients with diabetes, neuropathy is likely the culmination of multiple chronic insults to the nervous system, including hyperglycemia, microvascular insufficiency, oxidative stress, and autoimmunity [1,3,4]. Risk increases with advancing age and duration of diabetes, poor glycemic control, high body mass index (BMI), and comorbid conditions such as hypertension. While the prevalence of PN varies according to the types of criteria used for diagnosis, population demographics, stage of disease, and other variables, database reviews and meta-analyses estimate that between 30% and 70% of PWH and 10% and 90% diabetes cases are complicated by PN at any given time [4]. The most common type of PN among patients with HIV or diabetes is distal sensory peripheral neuropathy (DSPN), also called distal symmetric polyneuropathy, characterized by progressive dysfunction of length-dependent sensory peripheral nerves [1,4-9]. Damage to largeand small-fiber neural networks cause a range of symptoms starting in the toes and feet, such as tingling, prickling, and discomfort, that increase over time in a symmetric, bilateral "stocking-glove" distribution involving the legs, hands, and arms. Symptoms may be accompanied by pain, either at disease onset or later in the course, typically described as burning, aching, shooting, or electrical [1].
周围神经病变(PN)是由感觉和运动周围神经损伤引起的HIV感染和糖尿病的一种严重的、经常使人衰弱的并发症。在HIV感染者(PWH)中,神经病变被认为是由高活性抗逆转录病毒疗法(HAART)神经毒性引起的,特别是司他夫定(d4T)、二脱氧胞苷(ddC)和去羟诺西碱(ddI),HIV的影响,或两者兼而有之[1]。高龄、身高较高(作为神经元轴突较长的指标)、合并糖尿病和核苷酸逆转录酶抑制剂(NRTI)治疗增加了PN风险[2]。在糖尿病患者中,神经病变可能是神经系统多种慢性损伤的结果,包括高血糖、微血管功能不全、氧化应激和自身免疫[1,3,4]。风险随着年龄的增长和糖尿病的持续时间、血糖控制不佳、高体重指数(BMI)和高血压等共病的增加而增加。虽然PN的患病率因诊断标准类型、人口统计学、疾病分期和其他变量而异,但数据库审查和荟萃分析估计,在任何给定时间,30%至70%的PWH和10%至90%的糖尿病病例都因PN而复杂[4]。HIV或糖尿病患者中最常见的PN类型是远端感觉周围神经病变(DSPN),也称为远端对称性多发性神经病,其特征是长度依赖性感觉周围神经的进行性功能障碍[1,49]。大小纤维神经网络的损伤会导致从脚趾和脚开始的一系列症状,如刺痛、刺痛和不适,这些症状会随着时间的推移而增加,呈对称的双侧“袜子手套”分布,包括腿、手和手臂。症状可能伴随疼痛,无论是在疾病发作时还是在病程后期,通常被描述为烧灼、疼痛、刺痛或电击[1]。
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引用次数: 0
Sirolimus for Treatment of β-Thalassemia: From Pre-Clinical Studies to the Design of Clinical Trials 西罗莫司治疗β-地中海贫血:从临床前研究到临床试验设计
Pub Date : 2021-01-01 DOI: 10.31488/heph.165
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引用次数: 9
The Shortage of Medical Providers Is a Pandemic 医疗服务提供者的短缺是一种流行病
Pub Date : 2021-01-01 DOI: 10.31488/heph.167
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引用次数: 0
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Health education and public health
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