铁下垂相关的长非编码RNA在泌尿系肿瘤中的作用

Wen-chao Xie, Jie Gu, Zhenqian Qin, Yimin Xie
{"title":"铁下垂相关的长非编码RNA在泌尿系肿瘤中的作用","authors":"Wen-chao Xie, Jie Gu, Zhenqian Qin, Yimin Xie","doi":"10.32948/auo.2023.01.20","DOIUrl":null,"url":null,"abstract":"Ferroptosis is a type of programmed cell death that has been recent topic of interest in cancer therapy. Growing evidence indicates that long noncoding RNAs (lncRNAs) are involved in ferroptosis and associated with the incidence and progression of cancer. However, the relationship between lncRNA and ferroptosis in urologic cancers has not been fully elucidated. In this review, we summarize ferroptosis-related lncRNAs (frlncRNAs) in urologic cancers. Studies indicate that frlncRNAs are associated with cancer metabolism, tumor microenvironment, and immune cell infiltration. In addition, frlncRNAs could regulate ferroptosis related genes both at the mRNA and protein level. Therefore, a deep understanding of the roles of frlncRNAs in urologic cancers occurrence and progression will provide novel information for the development of anticancer therapies.","PeriodicalId":33190,"journal":{"name":"Annals of Urologic Oncology","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Roles of Ferroptosis-related Long Non-coding RNAs in Urologic Cancers\",\"authors\":\"Wen-chao Xie, Jie Gu, Zhenqian Qin, Yimin Xie\",\"doi\":\"10.32948/auo.2023.01.20\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Ferroptosis is a type of programmed cell death that has been recent topic of interest in cancer therapy. Growing evidence indicates that long noncoding RNAs (lncRNAs) are involved in ferroptosis and associated with the incidence and progression of cancer. However, the relationship between lncRNA and ferroptosis in urologic cancers has not been fully elucidated. In this review, we summarize ferroptosis-related lncRNAs (frlncRNAs) in urologic cancers. Studies indicate that frlncRNAs are associated with cancer metabolism, tumor microenvironment, and immune cell infiltration. In addition, frlncRNAs could regulate ferroptosis related genes both at the mRNA and protein level. Therefore, a deep understanding of the roles of frlncRNAs in urologic cancers occurrence and progression will provide novel information for the development of anticancer therapies.\",\"PeriodicalId\":33190,\"journal\":{\"name\":\"Annals of Urologic Oncology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Urologic Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32948/auo.2023.01.20\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Urologic Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32948/auo.2023.01.20","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

脱铁症是一种程序性细胞死亡,最近在癌症治疗中引起了人们的兴趣。越来越多的证据表明,长非编码RNA(lncRNA)参与脱铁性贫血,并与癌症的发病率和进展有关。然而,lncRNA与泌尿系癌症脱铁症之间的关系尚未完全阐明。在这篇综述中,我们总结了泌尿系统癌症中与脱铁相关的lncRNA(frlncRNA)。研究表明frlncRNA与癌症代谢、肿瘤微环境和免疫细胞浸润有关。此外,frlncRNA可以在mRNA和蛋白质水平上调节脱铁相关基因。因此,深入了解frlncRNA在泌尿系统癌症发生和发展中的作用,将为开发抗癌疗法提供新的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The Roles of Ferroptosis-related Long Non-coding RNAs in Urologic Cancers
Ferroptosis is a type of programmed cell death that has been recent topic of interest in cancer therapy. Growing evidence indicates that long noncoding RNAs (lncRNAs) are involved in ferroptosis and associated with the incidence and progression of cancer. However, the relationship between lncRNA and ferroptosis in urologic cancers has not been fully elucidated. In this review, we summarize ferroptosis-related lncRNAs (frlncRNAs) in urologic cancers. Studies indicate that frlncRNAs are associated with cancer metabolism, tumor microenvironment, and immune cell infiltration. In addition, frlncRNAs could regulate ferroptosis related genes both at the mRNA and protein level. Therefore, a deep understanding of the roles of frlncRNAs in urologic cancers occurrence and progression will provide novel information for the development of anticancer therapies.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
5
审稿时长
4 weeks
期刊最新文献
Clinical Features and Significance of Malignant Priapism Research Progress on the Association between Obesity and Prostate Cancer Exploration of Apoptosis in Histopathologies of Balkan Endemic Nephropathies with Both Urothelial Tumour and Atrophied Kidney The relationship between vitamin D, chronic kidney disease, and mineral and bone disorder: a complex interplay comprehensive review Incidental Detection of Papillary Renal Cell Carcinoma in Nephrectomy Specimen for Chronic Pyelonephritis
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1