{"title":"构建跨器官的全身代谢跨体网络","authors":"Toshiya Kokaji , Shinya Kuroda","doi":"10.1016/j.coemr.2022.100361","DOIUrl":null,"url":null,"abstract":"<div><p>Systemic metabolism is regulated by inter-organ communication at the whole-body level, and at the intra-organ level, there are also numerous factors involved in metabolic regulation. Transomic analysis is used to construct a metabolic regulatory network by integrating multiple factors obtained by multiomic analysis with interaction information. This review provides an overview of multiomic technologies and databases for intra- and inter-organ interactions, and discusses methods for constructing inter-organ transomic networks and their applications.</p></div>","PeriodicalId":52218,"journal":{"name":"Current Opinion in Endocrine and Metabolic Research","volume":"25 ","pages":"Article 100361"},"PeriodicalIF":0.0000,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Construction of an inter-organ transomic network for whole-body metabolism\",\"authors\":\"Toshiya Kokaji , Shinya Kuroda\",\"doi\":\"10.1016/j.coemr.2022.100361\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Systemic metabolism is regulated by inter-organ communication at the whole-body level, and at the intra-organ level, there are also numerous factors involved in metabolic regulation. Transomic analysis is used to construct a metabolic regulatory network by integrating multiple factors obtained by multiomic analysis with interaction information. This review provides an overview of multiomic technologies and databases for intra- and inter-organ interactions, and discusses methods for constructing inter-organ transomic networks and their applications.</p></div>\",\"PeriodicalId\":52218,\"journal\":{\"name\":\"Current Opinion in Endocrine and Metabolic Research\",\"volume\":\"25 \",\"pages\":\"Article 100361\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Opinion in Endocrine and Metabolic Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2451965022000461\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Endocrine and Metabolic Research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2451965022000461","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Construction of an inter-organ transomic network for whole-body metabolism
Systemic metabolism is regulated by inter-organ communication at the whole-body level, and at the intra-organ level, there are also numerous factors involved in metabolic regulation. Transomic analysis is used to construct a metabolic regulatory network by integrating multiple factors obtained by multiomic analysis with interaction information. This review provides an overview of multiomic technologies and databases for intra- and inter-organ interactions, and discusses methods for constructing inter-organ transomic networks and their applications.