构建跨器官的全身代谢跨体网络

Toshiya Kokaji , Shinya Kuroda
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引用次数: 0

摘要

全身代谢在全身水平上受器官间通讯的调节,在器官内水平上,参与代谢调节的因素也很多。跨体分析是将多组学分析得到的多个因子与相互作用信息相结合,构建代谢调控网络。本文综述了多组学技术和器官间相互作用数据库的研究进展,并讨论了构建器官间跨体网络的方法及其应用。
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Construction of an inter-organ transomic network for whole-body metabolism

Systemic metabolism is regulated by inter-organ communication at the whole-body level, and at the intra-organ level, there are also numerous factors involved in metabolic regulation. Transomic analysis is used to construct a metabolic regulatory network by integrating multiple factors obtained by multiomic analysis with interaction information. This review provides an overview of multiomic technologies and databases for intra- and inter-organ interactions, and discusses methods for constructing inter-organ transomic networks and their applications.

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来源期刊
Current Opinion in Endocrine and Metabolic Research
Current Opinion in Endocrine and Metabolic Research Medicine-Endocrinology, Diabetes and Metabolism
CiteScore
4.10
自引率
0.00%
发文量
80
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