昼夜节律在睡眠障碍中的作用研究进展

IF 0.3 Q4 PHARMACOLOGY & PHARMACY Current Drug Therapy Pub Date : 2023-08-18 DOI:10.2174/1574885518666230818102714
Namra Aziz, V. Garg, Yadav Rupali Vinod, Arpit Gupta, A. Wal, Shruti Rathore, P. Wal
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引用次数: 0

摘要

对睡眠-觉醒周期管理的分子、细胞和生物学机制的理解,以及昼夜节律紊乱对健康和疾病的影响,已经取得了重大进展。从Scopus、Elsevier和PubMed等标准数据库中使用标准关键词“昼夜节律”和“睡眠障碍”进行了广泛的文献综述。在本节中,我们研究了昼夜节律生物学,并对临床实践中最典型的昼夜节律性睡眠障碍(CRSD)的发病机制、临床特征、诊断和管理进行了详细描述。可以得出结论,中枢昼夜节律机制可能发生改变,或者内在的昼夜节律时钟和环境可能不同步,从而产生昼夜节律睡眠障碍。因此,我们必须专注于以建设性和健康的方式改变我们的生活方式。尽管生活方式是基于个人偏好和身份的,但重要的是要将其与社会文化环境隔离开来
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An Update On The Role Of Circadian Rhythms In Sleep Disorders
The comprehension of the molecular, cellular, and biological mechanisms that underlie the management of the sleep-wake cycle, as well as the effects of circadian disruption on health and illness, has made significant strides. An extensive literature review was done from the standard databases such as Scopus, Elsevier, and PubMed using standard keywords “Circadian rhythm”, and “sleep disorders”. In this section, we examined circadian biology and provided adetailed description of the pathogenesis, clinical characteristics, diagnosis, and management of the most typical Circadian rhythm sleep disorders (CRSDs) seen in clinical practice. It can be concluded that the central circadian rhythm mechanism may be altered, or the intrinsic circadian clock and the environment may not be in sync, to produce circadian rhythm sleep disorders. As a consequence, we must focus on modifying our way of life in a constructive and healthy way. Even while the lifestyle is based on personal preferences and identities, it is important to examine it in isolation from its sociocultural environment
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来源期刊
Current Drug Therapy
Current Drug Therapy PHARMACOLOGY & PHARMACY-
CiteScore
1.30
自引率
0.00%
发文量
50
期刊介绍: Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.
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