肢端肥大症护理的连续性:手术干预后复发的检测和管理

IF 1 Q3 MEDICINE, GENERAL & INTERNAL Electronic Journal of General Medicine Pub Date : 2023-09-01 DOI:10.29333/ejgm/13293
Alia Fahizha Fahimi, Juliawati Muhammad, F. Mohd Zin, Nur Suhaila Idris
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引用次数: 0

摘要

肢端肥大症是一种罕见的疾病,初级保健团队正在对其进行随访。它通常是由垂体腺瘤引起的,治疗方法是切除肿瘤。但是手术干预是肢端肥大症患者治疗的终点吗?这一病例突出了一位65岁的绅士的连续护理,他从31岁起就被诊断为肢端肥大症。他在45岁时接受了垂体腺瘤的经中隔蝶窦切除术。术后仍有残留的生长激素(GH)和胰岛素样生长因子(IGF-1)分泌物。然而,在术后20年的随访中,尽管GH和IGF-1水平不断升高,但由于治疗重点转向了他的另一个医疗问题,即糖尿病和心房颤动,肢端肥大症的治疗被忽视了。在最近的一次随访中,他抱怨头痛,并对病情复发表示担忧。重复的GH水平显示其水平增加,并推测有可能复发肢端肥大症。该病例强调了在手术干预后识别GH和IGF-1水平的重要性,以便通过初级保健和早期转诊到内分泌团队来检测复发性肢端肥大症。
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Continuity of care in acromegaly: Detecting and managing recurrence after surgical intervention
Acromegaly is a rare disease being followed up by primary care team. It is usually caused by pituitary adenoma and the treatment would be resection of the tumour. But is surgical intervention the end of treatment for acromegalic patient? This case highlighted the continuity of care in a 65-year old gentleman who had been diagnosed acromegaly since the age of 31. He had undergone a transseptal transsphenoidal resection of his pituitary adenoma when he was 45-year-old. Postoperatively, there were still residual growth hormone (GH) and insulin like growth factor (IGF-1) secretions. However, during 20 years follow up after operation, despite the increasing level of GH and IGF-1, the management of acromegaly were neglected as the focus of treatment were shifted towards his other medical problem, which is diabetes and atrial fibrillation. During his latest follow up, his complaint of unspecified headache and expressed his worry regarding the recurrence of his condition. Repeated GH level showed an increase in its level and postulated the possibility of recurrent acromegaly. This case emphasizes the important of recognizing the level of GH and IGF-1 after surgical intervention in order to detect recurrence acromegaly by primary care and early referral to endocrine team.
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来源期刊
Electronic Journal of General Medicine
Electronic Journal of General Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
3.60
自引率
4.80%
发文量
79
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