Janat M Alsaif, Zainab S Alali, Tarek El Sharkawy, Ayesha Ahmed, A. S. Awadalla, Methal I AlBayat, Wejdan N Almotairi
Primary pulmonary enteric adenocarcinoma (P-PEAC) is an unusual subtype of invasive lung adenocarcinoma. The significance of such tumor lies in its similar histopathological and immunohistochemical characteristics to colorectal adenocarcinoma. Therefore, a detailed investigation is crucial to establish a definitive diagnosis. This paper reports a case of a 51-year-old Saudi female, diagnosed with a rare variant of lung carcinoma, P-PEAC.
{"title":"Primary pulmonary enteric adenocarcinoma: A case report and review of literature","authors":"Janat M Alsaif, Zainab S Alali, Tarek El Sharkawy, Ayesha Ahmed, A. S. Awadalla, Methal I AlBayat, Wejdan N Almotairi","doi":"10.29333/ejgm/14785","DOIUrl":"https://doi.org/10.29333/ejgm/14785","url":null,"abstract":"Primary pulmonary enteric adenocarcinoma (P-PEAC) is an unusual subtype of invasive lung adenocarcinoma. The significance of such tumor lies in its similar histopathological and immunohistochemical characteristics to colorectal adenocarcinoma. Therefore, a detailed investigation is crucial to establish a definitive diagnosis. This paper reports a case of a 51-year-old Saudi female, diagnosed with a rare variant of lung carcinoma, P-PEAC.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141663898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E.V. Parshina, Alexey Zulkarnaev, A. Tolkach, Andrey Ivanov, P. Kislyy
Purpose: The aim of this study is to assess long-term immunogenicity of the recombinant adenoviruses 26 and 5 vector-based COVID-19 vaccine Gam-COVID-Vac (Sputnik V, developed by N. F. Gamaleya National Research Centre, Russia) in patients receiving maintenance hemodialysis (HD) compared to healthy subjects. Materials & methods: A prospective cohort study included patients treated with maintenance HD (n=23) and healthy volunteers (n=28). The levels of anti-severe acute respiratory syndrome coronavirus-2 specific IgG as well as specific T-cell responses were quantified in all participants at two time points: one and six months after complete vaccination. All participates were adults, had been vaccinated twice with Gam-COVID-Vac and had no prior history of confirmed COVID-19. Results: In both groups, IgG levels decreased from month one to six, however, antibodies did not decline more rapidly in HD group (analysis of variance p=0.7214 for the “time×group” interaction, non-adjusted model). At the end of the study, 48.0% of non-HD and 67.0% of HD participants showed T-cell positivity. T-spot counts dropped over time in non-HD controls, but not in HD subjects (p=0.0080 and p=0.1800, respectively). Conclusions: Patients receiving HD maintain significant long-term humoral response after Gam-COVID-Vac vaccination, which is comparable to that in subjects with normal kidney function. Cellular response turned up to be more sustained over time in HD group.
目的：本研究旨在评估基于重组腺病毒 26 和 5 载体的 COVID-19 疫苗 Gam-COVID-Vac （Sputnik V，由俄罗斯 N. F. Gamaleya 国家研究中心开发）在接受维持性血液透析（HD）的患者中与健康受试者相比的长期免疫原性：前瞻性队列研究包括接受维持性血液透析治疗的患者（23 人）和健康志愿者（28 人）。所有参与者的抗严重急性呼吸系统综合征冠状病毒-2 特异性 IgG 和特异性 T 细胞反应水平在两个时间点进行了量化：完全接种疫苗后的 1 个月和 6 个月。所有参与者均为成年人，接种过两次 Gam-COVID-Vac 疫苗，且之前没有确诊过 COVID-19 的病史：结果：两组的 IgG 水平从第 1 个月到第 6 个月都有所下降，但 HD 组的抗体下降速度并没有更快（"时间×组 "交互作用的方差分析 p=0.7214，非调整模型）。研究结束时，48.0% 的非 HD 参与者和 67.0% 的 HD 参与者显示出 T 细胞阳性。随着时间的推移，非 HD 对照组的 T 点计数下降，但 HD 受试者的 T 点计数没有下降（分别为 p=0.0080 和 p=0.1800）：结论：接种 Gam-COVID-Vac 疫苗后，接受 HD 治疗的患者长期保持明显的体液反应，与肾功能正常的受试者相当。血液透析组的细胞反应更持久。
{"title":"Long-term humoral and cellular responses elicited by Gam-COVID-Vac vaccine in hemodialysis patients: A prospective cohort study","authors":"E.V. Parshina, Alexey Zulkarnaev, A. Tolkach, Andrey Ivanov, P. Kislyy","doi":"10.29333/ejgm/14786","DOIUrl":"https://doi.org/10.29333/ejgm/14786","url":null,"abstract":"Purpose: The aim of this study is to assess long-term immunogenicity of the recombinant adenoviruses 26 and 5 vector-based COVID-19 vaccine Gam-COVID-Vac (Sputnik V, developed by N. F. Gamaleya National Research Centre, Russia) in patients receiving maintenance hemodialysis (HD) compared to healthy subjects.\u0000Materials & methods: A prospective cohort study included patients treated with maintenance HD (n=23) and healthy volunteers (n=28). The levels of anti-severe acute respiratory syndrome coronavirus-2 specific IgG as well as specific T-cell responses were quantified in all participants at two time points: one and six months after complete vaccination. All participates were adults, had been vaccinated twice with Gam-COVID-Vac and had no prior history of confirmed COVID-19.\u0000Results: In both groups, IgG levels decreased from month one to six, however, antibodies did not decline more rapidly in HD group (analysis of variance p=0.7214 for the “time×group” interaction, non-adjusted model). At the end of the study, 48.0% of non-HD and 67.0% of HD participants showed T-cell positivity. T-spot counts dropped over time in non-HD controls, but not in HD subjects (p=0.0080 and p=0.1800, respectively).\u0000Conclusions: Patients receiving HD maintain significant long-term humoral response after Gam-COVID-Vac vaccination, which is comparable to that in subjects with normal kidney function. Cellular response turned up to be more sustained over time in HD group.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141666190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amr Hemeda Mustafa, Mahmoud Mohammed Mahmoud Saber, Hosny Abdel Kareem Ahmed Mahmoud, Mostafa Abd Elazeem Hassan Ahamed, Ahmed Hagag Ismail Ahmed, Mohammed Fawzy Fouad, Ahmed Mohammed Farid EL-Moazen, Abd El-Monem M Hassan, Ahmed Ibrahim Mostafa, Ahmed Abady Ahmed Ali, Ahmed Ali Faheem Abdo, Al-Hussein Mustafa Zahran, A. Almarghany, Moustafa Mohamed Eldeib, Abdelhamid Ismail Abdelhamid Abu Rahhal, Ahmed Saadeldeen Ibrahem Mansour, Ashraf Yahia Abdel Elgawad, Ali Elsayed Ali Elagamy, El Sayed Hamed Fahmy, Khalid A Rashed, Ehab Ibrahim Sorour
Aim: The purpose of this research was to contrast (heart-rate corrected QT interval) QTc, and (QT dispersion) QTd intervals in individuals with (temporal lobe epilepsy) TLE and those without TLE using a standard 12-lead electrocardiogram. Patients & methods: This cross-sectional research was undertaken on 100 cases aged 10 to 20 diagnosed with epilepsy in accordance with 2017 ILAE criteria. The patients’ informed written permission was acquired. In our study, we included 100 cases: 50 with TLE and 50 with non-TLE verified by seizure semiology. All patients were subjected to a comprehensive history, clinical examination (heart rate, pulse, and blood pressure), and clinical evaluation, which included a comprehensive epilepsy history. On the basis of neurology service documents or the initial publication of the international classification of diseases, 9th revision (ICD9) diagnostic or 10th revision (ICD10) codes for epilepsy, diagnostic age for epilepsy was calculated. Results: The mean QT interval in group I was 418.30±25.48 ms while that of group II was 406.20±27.63 ms, the mean QTc of group I was 513.60±61.94 ms and was 488.70±50.65 in group II. The calculated QTd was with a mean of 57.60±25.05 ms while that of group II was 43.60±31.89 ms. It means that the QT interval, QTc, and QTd values were considerably greater in the group I (temporal epilepsy) contrasted with group II (non-temporal epilepsy); (p=0.025, 0.030, and 0.016, respectively). The mean QT, QTc, and QTd values for FE were 409.20±20.80, 500.70±55.60, and 52.60±29.70 ms, respectively. QT, QTc, and QTd mean values for patients with widespread epilepsy were 412.00±25.60, 505.00±68.60, and 46.20±28.70 ms. QT, QTc, and QTd interval were insignificantly different between focal and generalized epilepsy. The longer an illness progresses, the longer the QT and QTc intervals, as there was a substantial positive correlation among illness’s course and QT interval (r=0.391, p<0.001) and QTc interval (r=0.289, p=0.011), but there was no noticeable impact on QTd due to the illness’s duration, as we found an insignificant correlation among duration of illness and QTC and QTd. Conclusions: Our findings indicate that; QTc interval and QTd are longer in epilepsy cases more among TLE cases contrasted with non-TLE. Since there was no distinction among different epilepsy types (focal and generalized).
{"title":"Corrected QT interval and QT dispersion in temporal lobe epilepsy in children and adolescent","authors":"Amr Hemeda Mustafa, Mahmoud Mohammed Mahmoud Saber, Hosny Abdel Kareem Ahmed Mahmoud, Mostafa Abd Elazeem Hassan Ahamed, Ahmed Hagag Ismail Ahmed, Mohammed Fawzy Fouad, Ahmed Mohammed Farid EL-Moazen, Abd El-Monem M Hassan, Ahmed Ibrahim Mostafa, Ahmed Abady Ahmed Ali, Ahmed Ali Faheem Abdo, Al-Hussein Mustafa Zahran, A. Almarghany, Moustafa Mohamed Eldeib, Abdelhamid Ismail Abdelhamid Abu Rahhal, Ahmed Saadeldeen Ibrahem Mansour, Ashraf Yahia Abdel Elgawad, Ali Elsayed Ali Elagamy, El Sayed Hamed Fahmy, Khalid A Rashed, Ehab Ibrahim Sorour","doi":"10.29333/ejgm/14787","DOIUrl":"https://doi.org/10.29333/ejgm/14787","url":null,"abstract":"Aim: The purpose of this research was to contrast (heart-rate corrected QT interval) QTc, and (QT dispersion) QTd intervals in individuals with (temporal lobe epilepsy) TLE and those without TLE using a standard 12-lead electrocardiogram.\u0000Patients & methods: This cross-sectional research was undertaken on 100 cases aged 10 to 20 diagnosed with epilepsy in accordance with 2017 ILAE criteria. The patients’ informed written permission was acquired. In our study, we included 100 cases: 50 with TLE and 50 with non-TLE verified by seizure semiology. All patients were subjected to a comprehensive history, clinical examination (heart rate, pulse, and blood pressure), and clinical evaluation, which included a comprehensive epilepsy history. On the basis of neurology service documents or the initial publication of the international classification of diseases, 9th revision (ICD9) diagnostic or 10th revision (ICD10) codes for epilepsy, diagnostic age for epilepsy was calculated.\u0000Results: The mean QT interval in group I was 418.30±25.48 ms while that of group II was 406.20±27.63 ms, the mean QTc of group I was 513.60±61.94 ms and was 488.70±50.65 in group II. The calculated QTd was with a mean of 57.60±25.05 ms while that of group II was 43.60±31.89 ms. It means that the QT interval, QTc, and QTd values were considerably greater in the group I (temporal epilepsy) contrasted with group II (non-temporal epilepsy); (p=0.025, 0.030, and 0.016, respectively). The mean QT, QTc, and QTd values for FE were 409.20±20.80, 500.70±55.60, and 52.60±29.70 ms, respectively. QT, QTc, and QTd mean values for patients with widespread epilepsy were 412.00±25.60, 505.00±68.60, and 46.20±28.70 ms. QT, QTc, and QTd interval were insignificantly different between focal and generalized epilepsy. The longer an illness progresses, the longer the QT and QTc intervals, as there was a substantial positive correlation among illness’s course and QT interval (r=0.391, p<0.001) and QTc interval (r=0.289, p=0.011), but there was no noticeable impact on QTd due to the illness’s duration, as we found an insignificant correlation among duration of illness and QTC and QTd.\u0000Conclusions: Our findings indicate that; QTc interval and QTd are longer in epilepsy cases more among TLE cases contrasted with non-TLE. Since there was no distinction among different epilepsy types (focal and generalized).","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141663845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The objective of this meta-analysis was to identify and quantify postpartum stress urinary incontinence (SUI) risk factors. Methods: We systemically searched three electronic databases (PubMed, Scopus, and Web of Science). The evaluated variables as risk factors were pooled as odds ratio (OR) with the corresponding 95% confidence intervals (CI). Results: 63 studies were included. The analysis found a significant positive association between SUI and vaginal delivery (OR=2.15), age (OR=1.44), BMI (OR=1.19), parity (OR=1.43), and fetal-birth weight (OR=1.08). Conclusions: Age, parity, delivery with forceps, birth weight, maternal body mass index, induction of labor, length of the second stage of labor, history of prenatal SUI, and vaginal delivery were all risk factors for postpartum SUI. Scientific novelty: This systematic review and meta-analysis provides the most comprehensive and updated evidence to date. Practical significance of the results: Healthcare personnel should be taught to recognize and treat postpartum SUI risk factors.
背景：这项荟萃分析的目的是确定和量化产后压力性尿失禁（SUI）的风险因素：本荟萃分析旨在确定和量化产后压力性尿失禁（SUI）的风险因素：我们系统检索了三个电子数据库（PubMed、Scopus 和 Web of Science）。结果：共纳入 63 项研究：结果：共纳入 63 项研究。分析发现，SUI 与阴道分娩（OR=2.15）、年龄（OR=1.44）、体重指数（OR=1.19）、胎次（OR=1.43）和胎儿出生体重（OR=1.08）呈显著正相关：结论：年龄、奇偶数、产钳助产、出生体重、产妇体重指数、引产、第二产程时间、产前 SUI 史和阴道分娩都是产后 SUI 的风险因素：结果的实用意义：医护人员应学会识别和治疗产后 SUI 的风险因素。
{"title":"Risk factors for postpartum stress urinary incontinence: An updated systematic review and meta-analysis","authors":"Ainura Veliyeva, Gulzhakhan Omarova, Tukaz Mustafazade, Islam Magalov, Amina Pulatova, Ravil Ibragimov","doi":"10.29333/ejgm/14780","DOIUrl":"https://doi.org/10.29333/ejgm/14780","url":null,"abstract":"Background: The objective of this meta-analysis was to identify and quantify postpartum stress urinary incontinence (SUI) risk factors.\u0000Methods: We systemically searched three electronic databases (PubMed, Scopus, and Web of Science). The evaluated variables as risk factors were pooled as odds ratio (OR) with the corresponding 95% confidence intervals (CI).\u0000Results: 63 studies were included. The analysis found a significant positive association between SUI and vaginal delivery (OR=2.15), age (OR=1.44), BMI (OR=1.19), parity (OR=1.43), and fetal-birth weight (OR=1.08).\u0000Conclusions: Age, parity, delivery with forceps, birth weight, maternal body mass index, induction of labor, length of the second stage of labor, history of prenatal SUI, and vaginal delivery were all risk factors for postpartum SUI.\u0000Scientific novelty: This systematic review and meta-analysis provides the most comprehensive and updated evidence to date.\u0000Practical significance of the results: Healthcare personnel should be taught to recognize and treat postpartum SUI risk factors.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141664157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Asthma remains a major worldwide challenge, which threatens health and economies. The vast majority of asthmatics continue to experience uncontrolled asthma; thus, the need for enhancing patients’ awareness, targeting the behavior of both physicians and patients to reach optimal medications’ use is arising. Medication management review (MMR) service can be delivered by pharmacists to help resolve this dilemma. Aims: To assess the clinical and humanistic outcomes of MMR service for asthmatic patients in Jordan. Via this service, the pharmacist identifies treatment related problems (TRPs) and resolves them either directly or by sending the physician a letter with recommendations. Methods: A prospective randomized single blinded intervention-control study was conducted over 15 months, in outpatient clinics of public hospitals in Jordan. Asthmatics were recruited and randomized into intervention and control groups. MMR service was delivered for all patients by the researcher to identify patients’ TRPs based on updated guidelines. Recommendations were sent to intervention patients’ physician for resolution. Pharmacist level recommendations were resolved by pharmacist for the intervention patients. All patients were reassessed at three months. Results: Patients with asthma (n=152) were recruited, and 959 TRPs were identified at baseline with no significant differences between both groups. A significant decrease in TRPs was noticed for the intervention group at follow-up, going down from 6.540±1.685 at baseline to 2.800±0.924 TRP per patient at follow-up (p< 0.001). Regarding TRPs at three-month follow-up, a significant difference (intervention group: 2.800±0.924, control group: 5.920±1.679 control, p< 0.001). Conclusions: MMR service, which was delivered to asthma patients for the first time in Jordan proved successful in identifying and resolving TRPs for asthma patients. Such outcomes are beneficial in improving asthma control for asthma patients in Jordan.
{"title":"Investigating the value of medication management review for asthma patients: A randomized controlled study","authors":"Tahani Tawfiq Al-Bahnasi, I. Basheti","doi":"10.29333/ejgm/14728","DOIUrl":"https://doi.org/10.29333/ejgm/14728","url":null,"abstract":"Background: Asthma remains a major worldwide challenge, which threatens health and economies. The vast majority of asthmatics continue to experience uncontrolled asthma; thus, the need for enhancing patients’ awareness, targeting the behavior of both physicians and patients to reach optimal medications’ use is arising. Medication management review (MMR) service can be delivered by pharmacists to help resolve this dilemma.\u0000Aims: To assess the clinical and humanistic outcomes of MMR service for asthmatic patients in Jordan. Via this service, the pharmacist identifies treatment related problems (TRPs) and resolves them either directly or by sending the physician a letter with recommendations.\u0000Methods: A prospective randomized single blinded intervention-control study was conducted over 15 months, in outpatient clinics of public hospitals in Jordan. Asthmatics were recruited and randomized into intervention and control groups. MMR service was delivered for all patients by the researcher to identify patients’ TRPs based on updated guidelines. Recommendations were sent to intervention patients’ physician for resolution. Pharmacist level recommendations were resolved by pharmacist for the intervention patients. All patients were reassessed at three months.\u0000Results: Patients with asthma (n=152) were recruited, and 959 TRPs were identified at baseline with no significant differences between both groups. A significant decrease in TRPs was noticed for the intervention group at follow-up, going down from 6.540±1.685 at baseline to 2.800±0.924 TRP per patient at follow-up (p< 0.001). Regarding TRPs at three-month follow-up, a significant difference (intervention group: 2.800±0.924, control group: 5.920±1.679 control, p< 0.001).\u0000Conclusions: MMR service, which was delivered to asthma patients for the first time in Jordan proved successful in identifying and resolving TRPs for asthma patients. Such outcomes are beneficial in improving asthma control for asthma patients in Jordan.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141344108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siti Asiah Ahmad Sabri, Juliawati Muhammad, R. Muhamad
Abdominal pain is a common presenting complaint in a primary care setting. Umbilical discharge secondary to umbilical anomalies is usually diagnosed in children and is rare in adults. This case highlights the possibilities of umbilical anomalies as causes of undifferentiated abdominal pain and umbilical discharge in adults. A 24-year-old male presented with a recurrent history of undifferentiated lower abdominal pain and umbilical discharge but was not diagnosed appropriately, leading to multiple visits to general practitioners and emergency departments for four years. An abdominal ultrasound was done, which revealed a hypoechoic tubular structure at the midline of the abdomen. A diagnosis of patent urachus was made and he was then referred to the surgical team for excision of the patent urachus.
{"title":"Infected patent urachus in a young male: Primary care perspective","authors":"Siti Asiah Ahmad Sabri, Juliawati Muhammad, R. Muhamad","doi":"10.29333/ejgm/14703","DOIUrl":"https://doi.org/10.29333/ejgm/14703","url":null,"abstract":"Abdominal pain is a common presenting complaint in a primary care setting. Umbilical discharge secondary to umbilical anomalies is usually diagnosed in children and is rare in adults. This case highlights the possibilities of umbilical anomalies as causes of undifferentiated abdominal pain and umbilical discharge in adults. A 24-year-old male presented with a recurrent history of undifferentiated lower abdominal pain and umbilical discharge but was not diagnosed appropriately, leading to multiple visits to general practitioners and emergency departments for four years. An abdominal ultrasound was done, which revealed a hypoechoic tubular structure at the midline of the abdomen. A diagnosis of patent urachus was made and he was then referred to the surgical team for excision of the patent urachus.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141359005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamad Syamilah, M. N. Norhayati, S. S. Mohd Yusoff
Ectopic pregnancies within previous cesarean section scars are rare but potentially life-threatening complications. Diagnosis can be challenging, particularly in primary care settings, where the focus is often on routine primary care services. We present a case report of a patient who initially presented to a primary care clinic with non-specific symptoms of ectopic pregnancy and was referred to a tertiary center for incomplete miscarriage. It was found to be a viable ectopic pregnancy within a cesarean scar. This case highlights the importance of keeping an open mind in patients with a history of cesarean section and uterine manipulation procedures such as manually evacuating a retained placenta. It emphasizes prompt diagnosis and referral to a specialized healthcare facility.
{"title":"Viable cesarean scar pregnancy from primary care perspective: A case report","authors":"Mohamad Syamilah, M. N. Norhayati, S. S. Mohd Yusoff","doi":"10.29333/ejgm/14631","DOIUrl":"https://doi.org/10.29333/ejgm/14631","url":null,"abstract":"Ectopic pregnancies within previous cesarean section scars are rare but potentially life-threatening complications. Diagnosis can be challenging, particularly in primary care settings, where the focus is often on routine primary care services. We present a case report of a patient who initially presented to a primary care clinic with non-specific symptoms of ectopic pregnancy and was referred to a tertiary center for incomplete miscarriage. It was found to be a viable ectopic pregnancy within a cesarean scar. This case highlights the importance of keeping an open mind in patients with a history of cesarean section and uterine manipulation procedures such as manually evacuating a retained placenta. It emphasizes prompt diagnosis and referral to a specialized healthcare facility.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141100327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: To investigate the factors affecting adherence to antiretroviral therapy (ART) and the quality of life in people living with human immunodeficiency virus (HIV), with a focus on evaluating the mediating roles of positive self-care management (PSCM) and brain gym. Methods: This is a descriptive study with a cross-sectional design. The data collected from June to August 2023. There are 262 respondents selected through convenience sampling. We used various research instruments, including questionnaires, which have undergone validity and reliability testing. The data were analyzed using the SEM-PLS analysis method. Results: Our data analysis shows that condition factors, physical and social environmental factors, and individual and family factors affect HIV individuals’ PSCM and brain gym combination, ART adherence, and quality of life. Findings show that condition-specific factors indirectly affect antiretroviral drug adherence. This impact is mediated by PSCM and brain gym. Conclusions: Specific condition variables, namely complexity of the disease, barriers, and stability of conditions indirectly influence ART adherence, mediated through the combined influence of PSCM and brain gym. This finding suggests that to enhance adherence and the quality of life among PLHIV, it is important to adopt an approach that encompasses a range of internal and external individual factors.
{"title":"Factors related ART adherence and quality of life in PLHIV: Mediating role of positive self-care management and brain gym","authors":"Nusalam Nursalam, Tintin Sukartini, Khatijah Lim Abdullah, Misutarno Misutarno, Idyatul Hasanah","doi":"10.29333/ejgm/14597","DOIUrl":"https://doi.org/10.29333/ejgm/14597","url":null,"abstract":"Objectives: To investigate the factors affecting adherence to antiretroviral therapy (ART) and the quality of life in people living with human immunodeficiency virus (HIV), with a focus on evaluating the mediating roles of positive self-care management (PSCM) and brain gym.\u0000Methods: This is a descriptive study with a cross-sectional design. The data collected from June to August 2023. There are 262 respondents selected through convenience sampling. We used various research instruments, including questionnaires, which have undergone validity and reliability testing. The data were analyzed using the SEM-PLS analysis method.\u0000Results: Our data analysis shows that condition factors, physical and social environmental factors, and individual and family factors affect HIV individuals’ PSCM and brain gym combination, ART adherence, and quality of life. Findings show that condition-specific factors indirectly affect antiretroviral drug adherence. This impact is mediated by PSCM and brain gym.\u0000Conclusions: Specific condition variables, namely complexity of the disease, barriers, and stability of conditions indirectly influence ART adherence, mediated through the combined influence of PSCM and brain gym. This finding suggests that to enhance adherence and the quality of life among PLHIV, it is important to adopt an approach that encompasses a range of internal and external individual factors.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141001701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Farouk, Ehab M. Abdo, Sameh E Elimam, Waleed E Elshinawy, Abdelaziz A Abdelhafez, Lobna Kh Sakr, W. Abdo, Hayam Abdel-Tawab, Eman A Elhamrawy, Sahar Fares Ahmed, Shymaa Adel Ismael, Mahmoud Kamel Elawady, Samy Ibrahim Kamel, Rehab Elsheikh, Ayman Osama
Purpose: The present study aimed to provide our experience with patch closure (PAC) and primary closure (PRC) after carotid endarterectomy (CEA). Materials & methods: The present retrospective comparative study included 106 patients submitted to elective CEA. They comprised 50 patients in PRC group and 56 patients in PAC group. Patients were followed perioperatively, at three months and at one year for surgical complications, stroke, and restenosis. Results: Postoperatively, no significant differences were found between the studied groups regarding rates of stroke (6.0% versus 3.6%, p=0.740), infection (0.0% versus 3.6%, p=0.520), hematoma (2.0% versus 1.8%, p=0.940), pseudoaneurysm (0.0% versus 3.6%, p=0.520), cranial nerve injury (2.0% versus 1.8%, p=0.940), and cardiac events (2.0% versus 1.8%, p=0.940). At three months, three patients in PRC group and four in PAC group were lost to follow up. No significant differences were found between the studied groups regarding rate of restenosis at three months (2.1% versus 0.0%, p=0.960). At one year, patients in PRC group experienced significantly higher rate of restenosis (14.9% versus 1.9%, p=0.046). None of the studied patients died. Conclusions: CEA combined with patch angioplasty may be associated with lower restenosis rate.
{"title":"Primary versus patch closure after carotid endarterectomy: A retrospective study","authors":"N. Farouk, Ehab M. Abdo, Sameh E Elimam, Waleed E Elshinawy, Abdelaziz A Abdelhafez, Lobna Kh Sakr, W. Abdo, Hayam Abdel-Tawab, Eman A Elhamrawy, Sahar Fares Ahmed, Shymaa Adel Ismael, Mahmoud Kamel Elawady, Samy Ibrahim Kamel, Rehab Elsheikh, Ayman Osama","doi":"10.29333/ejgm/14596","DOIUrl":"https://doi.org/10.29333/ejgm/14596","url":null,"abstract":"Purpose: The present study aimed to provide our experience with patch closure (PAC) and primary closure (PRC) after carotid endarterectomy (CEA).\u0000Materials & methods: The present retrospective comparative study included 106 patients submitted to elective CEA. They comprised 50 patients in PRC group and 56 patients in PAC group. Patients were followed perioperatively, at three months and at one year for surgical complications, stroke, and restenosis.\u0000Results: Postoperatively, no significant differences were found between the studied groups regarding rates of stroke (6.0% versus 3.6%, p=0.740), infection (0.0% versus 3.6%, p=0.520), hematoma (2.0% versus 1.8%, p=0.940), pseudoaneurysm (0.0% versus 3.6%, p=0.520), cranial nerve injury (2.0% versus 1.8%, p=0.940), and cardiac events (2.0% versus 1.8%, p=0.940). At three months, three patients in PRC group and four in PAC group were lost to follow up. No significant differences were found between the studied groups regarding rate of restenosis at three months (2.1% versus 0.0%, p=0.960). At one year, patients in PRC group experienced significantly higher rate of restenosis (14.9% versus 1.9%, p=0.046). None of the studied patients died.\u0000Conclusions: CEA combined with patch angioplasty may be associated with lower restenosis rate.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140998831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Ben Salah, A. Derbel, Fatma Megdich, I. Chabchoub, C. Kallel, Zouhir Bahloul
Purposes: Retinal vein occlusion (RVO) is a major cause of vision loss. Its pathogenesis is still not completely understood. Our aim was to describe patients with RVO, to precise risk factors responsible to retinal vasculopathy in our population and to assess the prevalence of thrombophilia disorders patients with RVO, compared to population-based group of age- and sex-matched controls. Patients & methods: Our study was retrospective conducted from 1 January 2013, until 30 June 2019, including 57 patients with RVO compared to 105 controls patient’s age- and sex-matched free of any visual disorders. Among 57 RVO cases, 26 were men and 31 were women. Results: The mean age was 45.0±14.7 years. Among systemic and ocular risk factors for RVO we found hypertension in 12 patients (31.6%), dyslipidemia in four patients (10.5%), diabetes in four patients (10.5%), and smoking in six patients (16.2%). Three patients (9.7%) had glaucoma and two patients (6.5%) had diabetic retinopathy. Ophthalmology examination found unilateral RVO in 52 patients (91.0%) and bilateral RVO in five patients (11.1%). Retinal angiography showed ischemic signs in seven patients (18.4%). Non-ischemic RVO was retained in 31 cases (81.6%). Macular edema was present in 12 patients (38.7%). Six cases (19.4%) developed neovascular glaucoma and two cases (6.5%) presented reversible blindness. Measures of thrombophilia practiced in 57 patients revealed 13 abnormalities (22.8%): Isolated thrombophilia disorder in 11 patients (71.4%) and combined prothrombotic disorder in two others. Conclusions: Among systemic and ocular risk factors for RVO, we found hypertension in 12 patients (31.6%). Thrombophilia disorders were also common.
{"title":"Risk factor for retinal vein occlusion: A case control study","authors":"R. Ben Salah, A. Derbel, Fatma Megdich, I. Chabchoub, C. Kallel, Zouhir Bahloul","doi":"10.29333/ejgm/14574","DOIUrl":"https://doi.org/10.29333/ejgm/14574","url":null,"abstract":"Purposes: Retinal vein occlusion (RVO) is a major cause of vision loss. Its pathogenesis is still not completely understood. Our aim was to describe patients with RVO, to precise risk factors responsible to retinal vasculopathy in our population and to assess the prevalence of thrombophilia disorders patients with RVO, compared to population-based group of age- and sex-matched controls.\u0000Patients & methods: Our study was retrospective conducted from 1 January 2013, until 30 June 2019, including 57 patients with RVO compared to 105 controls patient’s age- and sex-matched free of any visual disorders. Among 57 RVO cases, 26 were men and 31 were women.\u0000Results: The mean age was 45.0±14.7 years. Among systemic and ocular risk factors for RVO we found hypertension in 12 patients (31.6%), dyslipidemia in four patients (10.5%), diabetes in four patients (10.5%), and smoking in six patients (16.2%). Three patients (9.7%) had glaucoma and two patients (6.5%) had diabetic retinopathy. Ophthalmology examination found unilateral RVO in 52 patients (91.0%) and bilateral RVO in five patients (11.1%). Retinal angiography showed ischemic signs in seven patients (18.4%). Non-ischemic RVO was retained in 31 cases (81.6%). Macular edema was present in 12 patients (38.7%). Six cases (19.4%) developed neovascular glaucoma and two cases (6.5%) presented reversible blindness. Measures of thrombophilia practiced in 57 patients revealed 13 abnormalities (22.8%): Isolated thrombophilia disorder in 11 patients (71.4%) and combined prothrombotic disorder in two others.\u0000Conclusions: Among systemic and ocular risk factors for RVO, we found hypertension in 12 patients (31.6%). Thrombophilia disorders were also common.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141006527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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