马来西亚吉隆坡青少年抑郁和自尊对自杀意念的预测作用

Chin Wen Cong, W. Ling
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引用次数: 8

摘要

简介:适宜的湿度、温度、不当的大米处理和储存会增加黄曲霉毒素在空气中生长的可能性。最常见和致癌的黄曲霉毒素是黄曲霉毒素B1(AFB1),如果吸入可能会导致肺癌。本研究旨在将AFB1在可吸入粉尘中的暴露及其对碾米工人呼吸系统的影响联系起来。材料和方法:这项横断面研究采用了有目的的抽样方法,招募了76名碾米工作为接触对象,48名办公室工作人员作为对照组。总的可吸入灰尘是使用装有过滤器的空气采样器收集的,暴露时间为8个工作小时。受试者的手在换班后用棉垫擦拭,棉垫用0.5ml磷酸盐缓冲盐水吐温-20溶液润湿。使用ELISA试剂盒对采集的样品进行AFB1分析。完成了收集社会人口统计、工作数据和呼吸道症状信息的问卷调查。在班前和班后进行肺功能测试。结果:碾米厂区域和个人暴露的平均空气AFB1分别为2.22 ng/m3±0.07和0.25 ng/m3±0.24。在两台碾米机上检测到手上AFB1的平均污染水平为0.25 ng/ml(2.3%),而在未接触的工人中检测不到。碾米工人抱怨最多的症状是喘息和呼吸困难(n=6,9.2%)。碾米工人和未接触碾米工人轮班前后的平均强迫呼气量(FEV1)存在显著差异,但平均AFB1浓度与肺功能之间没有显著相关性。年龄和工作因素是肺功能的混杂因素。结论:尽管本研究中没有建立关联,但强烈建议在碾米工人中提倡穿戴合适的个人防护装备(PPE),以防止累积接触。
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THE PREDICTING EFFECTS OF DEPRESSION AND SELFESTEEM ON SUICIDAL IDEATION AMONG ADOLESCENTS IN KUALA LUMPUR, MALAYSIA
Introduction: Optimal humidity, temperature, improper handling and storage of rice will increase the likeliness of aflatoxin growth in the air. The most common and carcinogenic aflatoxin is Aflatoxin B1 (AFB1) that may cause lung cancer if inhaled. This study aims to associate the exposure of AFB1 in inhalable dust and its respiratory effects among rice millers.  Materials and Methods: This cross-sectional study utilised the purposive sampling method and recruited 76 rice millers as exposed subjects and 48 office workers as the control group. The total inhalable dust was collected using the filter-loaded air samplers for an eight working hours’ exposure. The subjects’ hands were swabbed with cotton pads wetted with 0.5 ml Phosphate buffered Saline Tween-20 solution post shift. The collected samples were analysed for AFB1 by using the ELISA kits. The questionnaire gathering information on sociodemographic, work data and respiratory symptoms were completed. The lung function test was performed for the pre- and post-shifts.  Results: The mean airborne AFB1 at the rice mill area and personal exposure were 2.22 ng/m3 ± 0.07 and 0.25 ng/m3 ± 0.24, respectively. The mean contamination level of AFB1 on hands was 0.25 ng/ml detected on two rice millers (2.3%) while non-detectable in non-exposed workers. The most complained symptoms among rice millers were wheezing and breathlessness (n = 6, 9.2%). There was a significant difference in the mean forced expiration volume (FEV1) for pre- and post-shifts between rice millers and the non-exposed workers, but no significant correlation between the mean AFB1 concentration and lung function. Age and work factors were confounders in lung function.  Conclusion: Despite no association being established in this study, the promotion of wearing suitable personal protective equipment (PPE) is highly recommended to prevent cumulative exposure among the rice millers.
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