{"title":"两种消化道重建方式对胃癌根治性全胃切除术后患者生活质量及免疫营养状况的影响","authors":"Tianzhu He, Qiang Hu, Lucy M. Zhang","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.03.008","DOIUrl":null,"url":null,"abstract":"Objective \nTo compare the quality of life, nutritional status and immune function of gastric cancer patients with digestive tract reconstruction using Roux-en-Y anastomosis and uncut Roux-en-Y anastomosis after radical gastrectomy. \n \n \nMethods \n86 patients with gastric cancer were selected from May 2015 to June 2017 with radical total gastrectomy. According to the different ways of the reconstruction of the digestive tract, the patients were divided into URY group (non-severed group, 41 patients) and RY group (traditional group, 45 patients). The quality of life of the two groups was compared at 1 month, 3 months and 6 months after operation. The nutritional status of albumin, prealbumin, transferrin, hemoglobin, retinol binding protein and weight, as well as CD4+ lymphocyte, CD8+ lymphocyte, CD4+ / CD8+ ratio, IgG, IgM, IgA and other immune related indexes were observed at pre-operation and 1 month, 3 months and 6 months after operation. \n \n \nResults \nAs for quality of life, the score of diet limitation in group URY was significantly lower than that in group RY at 1 month after operation (P 0.05); As for anxiety, the score of group URY was higher than that in group RY (P 0.05). As for the nutritional indexes, prealbumin in the URY group was higher than that in the RY group at 6 months after operation (P 0.05). There was no statistical significance in immune indexes between the two groups (P>0.05). The postoperative hospitalization time of URY group was less than that of RY group (P 0.05). \n \n \nConclusion \nExcept for the length of hospitalization and postoperative complications in which uncut Roux-en-Y anastomosis was superior to Roux-en-Y anastomosis, there is no significant difference in quality of life and nutritional and immune indicators between the two alimentary tract reconstruction methods. \n \n \nKey words: \nGastric cancer; Digestive tract reconstruction; Quality of life; Nutrition; Immune","PeriodicalId":9877,"journal":{"name":"中华临床营养杂志","volume":"27 1","pages":"167-172"},"PeriodicalIF":0.0000,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Effects of two different reconstruction methods of digestive tract after radical total gastrectomy on quality of life and immune nutrition status in patients with gastric cancer\",\"authors\":\"Tianzhu He, Qiang Hu, Lucy M. Zhang\",\"doi\":\"10.3760/CMA.J.ISSN.1674-635X.2019.03.008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective \\nTo compare the quality of life, nutritional status and immune function of gastric cancer patients with digestive tract reconstruction using Roux-en-Y anastomosis and uncut Roux-en-Y anastomosis after radical gastrectomy. \\n \\n \\nMethods \\n86 patients with gastric cancer were selected from May 2015 to June 2017 with radical total gastrectomy. According to the different ways of the reconstruction of the digestive tract, the patients were divided into URY group (non-severed group, 41 patients) and RY group (traditional group, 45 patients). The quality of life of the two groups was compared at 1 month, 3 months and 6 months after operation. The nutritional status of albumin, prealbumin, transferrin, hemoglobin, retinol binding protein and weight, as well as CD4+ lymphocyte, CD8+ lymphocyte, CD4+ / CD8+ ratio, IgG, IgM, IgA and other immune related indexes were observed at pre-operation and 1 month, 3 months and 6 months after operation. \\n \\n \\nResults \\nAs for quality of life, the score of diet limitation in group URY was significantly lower than that in group RY at 1 month after operation (P 0.05); As for anxiety, the score of group URY was higher than that in group RY (P 0.05). As for the nutritional indexes, prealbumin in the URY group was higher than that in the RY group at 6 months after operation (P 0.05). There was no statistical significance in immune indexes between the two groups (P>0.05). The postoperative hospitalization time of URY group was less than that of RY group (P 0.05). \\n \\n \\nConclusion \\nExcept for the length of hospitalization and postoperative complications in which uncut Roux-en-Y anastomosis was superior to Roux-en-Y anastomosis, there is no significant difference in quality of life and nutritional and immune indicators between the two alimentary tract reconstruction methods. \\n \\n \\nKey words: \\nGastric cancer; Digestive tract reconstruction; Quality of life; Nutrition; Immune\",\"PeriodicalId\":9877,\"journal\":{\"name\":\"中华临床营养杂志\",\"volume\":\"27 1\",\"pages\":\"167-172\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中华临床营养杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.03.008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Nursing\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华临床营养杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.03.008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Nursing","Score":null,"Total":0}
Effects of two different reconstruction methods of digestive tract after radical total gastrectomy on quality of life and immune nutrition status in patients with gastric cancer
Objective
To compare the quality of life, nutritional status and immune function of gastric cancer patients with digestive tract reconstruction using Roux-en-Y anastomosis and uncut Roux-en-Y anastomosis after radical gastrectomy.
Methods
86 patients with gastric cancer were selected from May 2015 to June 2017 with radical total gastrectomy. According to the different ways of the reconstruction of the digestive tract, the patients were divided into URY group (non-severed group, 41 patients) and RY group (traditional group, 45 patients). The quality of life of the two groups was compared at 1 month, 3 months and 6 months after operation. The nutritional status of albumin, prealbumin, transferrin, hemoglobin, retinol binding protein and weight, as well as CD4+ lymphocyte, CD8+ lymphocyte, CD4+ / CD8+ ratio, IgG, IgM, IgA and other immune related indexes were observed at pre-operation and 1 month, 3 months and 6 months after operation.
Results
As for quality of life, the score of diet limitation in group URY was significantly lower than that in group RY at 1 month after operation (P 0.05); As for anxiety, the score of group URY was higher than that in group RY (P 0.05). As for the nutritional indexes, prealbumin in the URY group was higher than that in the RY group at 6 months after operation (P 0.05). There was no statistical significance in immune indexes between the two groups (P>0.05). The postoperative hospitalization time of URY group was less than that of RY group (P 0.05).
Conclusion
Except for the length of hospitalization and postoperative complications in which uncut Roux-en-Y anastomosis was superior to Roux-en-Y anastomosis, there is no significant difference in quality of life and nutritional and immune indicators between the two alimentary tract reconstruction methods.
Key words:
Gastric cancer; Digestive tract reconstruction; Quality of life; Nutrition; Immune
期刊介绍：
The Chinese Journal of Clinical Nutrition was founded in 1993. It is the first professional academic journal (bimonthly) in my country co-sponsored by the Chinese Medical Association and the Chinese Academy of Medical Sciences to disseminate information on clinical nutrition support, nutrient metabolism, the impact of nutrition support on outcomes and "cost-effectiveness", as well as translational medicine and nutrition research. It is also a professional journal of the Chinese Medical Association's Parenteral and Enteral Nutrition Branch.
The purpose of the Chinese Journal of Clinical Nutrition is to promote the rapid dissemination of knowledge on nutrient metabolism and the rational application of parenteral and enteral nutrition, focusing on the combination of multidisciplinary and multi-regional field investigations and clinical research. It mainly reports on nutritional risk screening related to the indications of parenteral and enteral nutrition support, "cost-effectiveness" research on nutritional drugs, consensus on clinical nutrition, guidelines, expert reviews, randomized controlled studies, cohort studies, glycoprotein and other nutrient metabolism research, systematic evaluation of clinical research, evidence-based case reports, special reviews, case reports and clinical experience exchanges, etc., and has a special column on new technologies related to the field of clinical nutrition and their clinical applications.
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