慢性中耳炎活动性粘膜型耳拭子抗生素敏感性及致病因素的研究

IF 0.1 Q4 OTORHINOLARYNGOLOGY Bangladesh Journal of Otorhinolaryngology Pub Date : 2021-11-01 DOI:10.3329/bjo.v27i2.56356
Md. Nesar Uddin, M. S. Islam, Mohammad Delwar Hossen, Mohammed Iftekharul Alam, M. K. Hossain
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引用次数: 1

摘要

背景:慢性中耳炎(COM)是指中耳裂粘骨膜衬里的慢性炎症,导致耳分泌物和耳聋。本研究的目的是评估COM的抗生素敏感性和病因因素。方法:本横断面研究于2017年7月至2018年6月在联合军事医院耳鼻喉科头颈外科就诊的COM活动性粘膜病患者中进行,为期一年。共有50例病例被隔离,其中5例患有双侧COM。从55只耳朵中提取耳拭子,并在预先设计的数据收集表中填写患者的社会经济状况信息。对每个病例的实验室记录进行了系统的整理。使用百分比和频率对数据进行简单的手动分析。结果:约24%的患者年龄在31-40岁之间。在50名患者中,62%为男性。44%的病人住在营房里。耳朵清洁习惯显示,32%的人有过用布和棍子清洁耳朵的习惯。在50例患者中,5例患有双侧COM。因此,在55耳中,培养和敏感性测试显示,铜绿假单胞菌是最主要的生物体,占41.8%,其次是金黄色葡萄球菌,占30.9%。抗生素敏感性谱显示,80%的病例对阿米卡星敏感,然后是庆大霉素73.3%。耐药的5例对他唑巴坦敏感。在19例革兰氏阳性菌中,78.9%对阿莫敏感。3例耐药病例对美罗培南的敏感性为100%。孟加拉国耳鼻喉科杂志2021;27(2):111-116
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Study of Antibiotic Sensitivity of Aural Swab and Aetiological Factors of Chronic Otitis Media-Active Mucosal Type
Background: Chronic otitis media (COM) refers to chronic inflammation of mucoperiosteal lining of middle ear cleft resulting in aural discharge and deafness. The objective of this study is to evaluate the antibiotic sensitivity and aetiological factors of COM. Methods: This cross-sectional study was conducted from July 2017 to June 2018 for duration of one year among the patients who attended with COM- active mucosal disease at Department of ENT & Head Neck Surgry, Combined Military Hospital (CMH) Chattogram. Total 50 cases were isolated and among them 5 cases had been suffering from bilateral COM. Aural swab was taken from 55 ears and a predesigned data collection sheet was duly filled up with the information of socioeconomic status of the patient. The laboratory records of every case was systematically organized. The data were analyzed with simple manual analysis using percentage and frequency. Results: About 24% patients were in 31-40 years age group. Out of 50 patients 62% were male. 44% patient lived in barrack. Ear cleaning habit shows, 32% has got the cleaning habit with cloth and stick. Out of 50 patients 5 had bilateral COM. So out of 55 ears, Culture & sensitivity test viewed that Pseudomonas aeruginosa was the most predominant organism - 41.8% followed by S. aureus- 30.9% Antibiotic sensitivity profile shows, 80% cases showing sensitivity to Amikacin then gentamycin-73.3% Resistant 5 cases showed 100% sensitivity to Tazobactum. Again out of 19 cases of Gram positive organism 78.9% were sensitive to Amoxyclav. 3 resistant cases showed 100% sensitivity to Meropenem. Conclusion: By studying this topic we hope to able to make an idea about the aetiological and predisposing factors and antibiotic sensitivity of COM-active mucosal variety. Bangladesh J Otorhinolaryngol 2021; 27(2): 111-116
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