应对COVID-19

B. Nepal
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摘要

2019年12月,严重急性呼吸综合征冠状病毒(SARS-CoV-2)首次出现在中国武汉。自那以后,它像野火一样在全球蔓延,在撰写本文时,已有超过500万冠状病毒病(COVID-19)确诊病例和近35万人死亡。然而,考虑到SARS-CoV-2病毒的传染性及其在全球传播的速度,这可能只是冰山一角。中国采取了严格的封锁措施,封锁疫区,积极发现病例,以惊人的速度追踪、追踪和治疗新冠肺炎病例,成功遏制了病毒。在缺乏特异性治疗的情况下,治疗主要包括一些实验性药物的症状管理。抗病毒药物,特别是雷姆德西韦,一直是治疗COVID-19的有力候选药物。然而,它尚未被普遍接受用于治疗COVID-19。氯喹和羟氯喹似乎可以有效地限制SARS-CoV-2病毒的体外复制。COVID-19在疟疾最不流行的国家高度流行,在疟疾高度流行的国家最不流行。这些发现支持了抗疟疾药物对COVID-19治疗有效的假设。
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Coping with COVID-19
Severe acute respiratory syndrome corona virus (SARS-CoV-2) virus made its first appearance in Wuhan, China in December 2019. It has since spread like a wild fire across the globe with over five million corona virus disease (COVID-19) confirmed cases and almost three hundred fifty thousand deaths at the time of writing this article. This could however be only the tip of the iceberg considering the contagious nature of the SARS-CoV-2 virus and the rate at which it is spreading across the globe. China did well to contain the virus with strict lockdown measures, sealing the affected areas, active case finding, tracing, tracking and treating the COVID-19 cases at an astonishing speed. In the absence of specific treatment available as yet, treatment consists of mainly symptomatic management with some experimental medications. Antivirals, specifically Remdesivir has been a strong candidate for the treatment of COVID-19. However, it has yet to receive universal acceptance for the treatment of COVID-19. Chloroquine and Hydroxychloroquine seem to be effective in limiting the replication of SARS-CoV-2 virus in vitro. COVID-19 is highly pandemic in countries where malaria is least prevalent and least pandemic in countries where malaria is highly prevalent. These findings suggest the hypothesis that anti-malarial drugs have efficacy in the treatment of COVID-19.
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