Advances in research of invasion and recurrence of pituitary adenoma

Pituitary adenoma, a common intracranial neuroendocrine tumor is usually a benign tumor, some of which are of invasiveness and high recurrence, making it a problem to be solved in neurosurgery. The clinical prognosis of pituitary adenoma is mainly determined by biological factors and clinical factors. In terms of biological factors, with the application of molecular array technology and others molecular detection progress in etiology and pathology, a lot of prediction, diagnosis, treatment related predictive factors and genes are detected for further screening. As for the other factors, standardized prognosis and treatment procedure and application of new technology are obvious in improving the prognosis of pituitary adenomas. This article reviews the research progress of the factors of pituitary adenoma, and provides the reference for the diagnosis and treatment of pituitary adenoma. DOI: 10.3969/j.issn.1672-6731.2017.07.011