颈动脉内膜切除术的初步闭合效果

Aamir Javid
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引用次数: 0

摘要

背景:脑血管缺血性病例是成人死亡和神经功能障碍的第三大原因。在近10-20%的病例中,颈动脉-颅内循环外的动脉粥样硬化病变是脑缺血的主要原因,颈动脉内膜切除术(CEA)已被证明对严重颈动脉狭窄的患者预防急性脑血管事件是有益的。本研究旨在评估研究期间我院患者颈动脉内膜切除术的发病率和死亡率的短期结果。材料和方法:这项横断面分析研究于2019年8月至2021年7月在拉瓦尔品第联合军事医院进行,以分析颈动脉内膜切除术(CEA)的短期疗效。所有在研究期间接受颈动脉内膜切除术(CEA)并初次闭合的患者均纳入研究。若脑电图(EEG)发生变化,接受选择性分流的患者被排除在研究之外。数据是在口头同意后通过预先准备的问卷收集的。在术后一个月内,观察到出血、感染、中风、短暂性脑缺血发作(TIA)、心肌梗死、重复手术和支架翻修等疾病的发生频率。还计算了颈动脉内膜切除术患者术后一个月的死亡率。数据输入并使用SPSS版本22进行分析。结果:在研究期间,共有198名患者接受了颈动脉内膜切除术并进行了一期闭合。研究参与者的年龄范围在35-80岁之间。男性患者107例(54.04%)。研究参与者评估的合并症显示,172例(86.87%)患者患有高血压,73例(36.87%)患有糖尿病。患者术后最常见的并发症是出血和重复手术。结论:颈动脉内膜切除术一期闭合是预防脑卒中安全有效的手术方法。
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Outcomes of Carotid Endarterectomy with Primary Closure
Background: Cerebrovascular ischemic cases are 3rd leading cause of fatality and neurologic dysfunction in adults. Atherosclerotic lesions outside the carotid cranial circulation are main cause of cerebral ischemia in almost 10-20 percent cases and carotid endarterectomy (CEA) has been proved beneficial for patients with severe carotid artery stenosis to prevent acute cerebrovascular events. Current study is conducted to assess the short-term outcomes of carotid endarterectomy among patients in terms of morbidities and mortalities at our institution during the study period. Material and Methods: This cross-sectional analytical study was carried out at Combined Military Hospital, Rawalpindi during August 2019 to July 2021 to analyze the short-term outcomes of carotid endarterectomy (CEA) with primary closure. All the patients who underwent carotid endarterectomy (CEA) with primary closure during study duration were included in the study. Patients who received selective shunting if Electro Encephalogram (EEG) changes noted were excluded from study. Data was collected after taking verbal consent by using preformed questionnaire. Frequency of morbidities like bleeding, infection, stroke, transient ischemic attacks (TIA), myocardial infarction, repeat operation and revision with stent were noted within postoperative period of one month. Frequency of mortalities in one-month postoperative period among patients undergoing carotid endarterectomy was also calculated. Data was entered and analyzed by using SPSS version 22. Results: Total 198 patients who underwent carotid endarterectomy with primary closure during study duration were included in the study. Age range of the study participants was between 35 to 80 years. Male patients were 107 (54.04%). The comorbidities evaluated in the study participants showed that 172 (86.87%) patients were hypertensive and 73 (36.87%) has diabetes mellitus. The most frequent postoperative morbidities among patients were bleeding and repeat operation. Conclusion: It is concluded that carotid endarterectomy with primary closure is a safe and effective surgical means of stroke prevention.
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