确定性和随机易感-感染-易感(SIS)和易感-感染-恢复(SIR)模型的比较

A. Moujahid, F. Vadillo
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引用次数: 1

摘要

本文建立并分析了两个有死亡的随机流行病模型。该模型假设只有易感个体(S)才会感染(I)并可能死于这种疾病,或者恢复后的个体再次易感(SIS模型)或在剩余的研究期间完全免疫(SIR模型)。此外,假定在研究期间没有出生、死亡、移民或移民;据说该社区已经关闭。在这些传染病模型中,有两个中心问题:第一是疾病是否灭绝,第二是研究这种灭绝所经过的时间,本文将处理第二个问题,因为第一个答案对应于参考书目中定义的基本繁殖数。更具体地说,我们研究了疾病的平均灭绝,这里使用的技术首先建立倒向Kolmogorov微分方程,然后用FreeFem++进行数值求解。我们的贡献和新颖之处在于:尽管繁殖数有效地判断了疾病的灭绝与否,但它并不能帮助我们知道疾病的灭绝时间,因为相同繁殖数的例子有非常不同的时间。此外,SIS模型较慢,这一结果并不令人惊讶,但相对于确定性模型,这种差异似乎在随机模型中有所增加,假设一些不确定性是合理的。
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A Comparison of Deterministic and Stochastic Susceptible-Infected-Susceptible (SIS) and Susceptible-Infected-Recovered (SIR) Models
In this paper we build and analyze two stochastic epidemic models with death. The model assumes that only susceptible individuals (S) can get infected (I) and may die from this disease or a recovered individual becomes susceptible again (SIS model) or completely immune (SIR Model) for the remainder of the study period. Moreover, it is assumed there are no births, deaths, immigration or emigration during the study period; the community is said to be closed. In these infection disease models, there are two central questions: first it is the disease extinction or not and the second studies the time elapsed for such extinction, this paper will deal with this second question because the first answer corresponds to the basic reproduction number defined in the bibliography. More concretely, we study the mean-extinction of the diseases and the technique used here first builds the backward Kolmogorov differential equation and then solves it numerically using finite element method with FreeFem++. Our contribution and novelty are the following: however the reproduction number effectively concludes the extinction or not of the disease, it does not help to know its extinction times because example with the same reproduction numbers has very different time. Moreover, the SIS model is slower, a result that is not surprising, but this difference seems to increase in the stochastic models with respect to the deterministic ones, it is reasonable to assume some uncertainly.
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