含氟取代吡唑并[3,4-d]嘧啶的多功能π-受体化合物和胍的新型杂环氮体系的合成

D. Bakhotmah, Salwa Y. Al-Hazme
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引用次数: 1

摘要

通过N’-杂芳基胍4与多功能π受体在不同介质和条件下的相互作用,合成了含有氟取代吡唑并[3,4-d]嘧啶部分的新型杂环氮体系。通过光谱分析确定了合成化合物的结构,并作为不同浓度的抗真菌探针进行了评价。
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Synthesis of Novel Heteropolycyclic Nitrogen Systems Bearing Fluorine Substituted Pyrazolo[3,4-d] Pyrimidine Derived from Polyfunctional π-Acceptor Compounds and Guanidine as Fungicidal Probes
Novel heteropolycyclic nitrogen systems bearing fluorine substituted pyrazolo[3,4-d] pyrimidine moiety have been synthesis by the interaction between N’-heteroaryl guanidine 4 with polyfunctional π-acceptors in different media and condition. The structures of the synthesis compounds were established by spectroscopic analysis and evaluated as antifungal probes in various concentration.
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