圣彼得堡男性HIV感染者和梅毒患者的社会形态、临床和流行病学特征

M. Chirskaya, E. Yastrebova, T. Krasnoselskikh, T. Vinogradova, E. B. Manasheva, N. V. Dunaeva
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摘要

目的声明旨在分析圣彼得堡GBUZ“艾滋病和传染病预防和控制中心”监督下的仅感染HIV的患者和同时感染HIV和梅毒螺旋体的患者的社会人口学、临床、流行病学和行为特征。材料和方法。对2018年至2020年期间在圣彼得堡中央临床中心药房登记的588名患者的门诊卡数据进行了研究,并选择了男性(435人)的卡数据。患者被分为两组:HIV单感染者(198人)和同时感染HIV和梅毒的患者(237人),与男性发生性关系的男性(同性恋)和双性恋男性更多。共同感染的患者现在或过去使用药物的可能性较小,主要通过性接触感染艾滋病毒。他们主要被诊断为早期梅毒。在合并感染的患者中,经常发现肾脏、心血管和内分泌系统的合并疾病,并且还注意到与慢性乙型肝炎的高度合并症。结论已确定的艾滋病毒+梅毒合并感染男性的社会人口统计学、临床、流行病学和行为特征表明,需要开展更积极的工作,在男性中普及屏障避孕,尤其是男男性行为者和易接触双性恋者;当在HIV感染的患者中检测到梅毒时,要对所有器官和系统进行彻底检查,特别是对病毒性肝炎的存在。
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Sociodemographic, clinical and epidemiological characteristics of the men with HIV infection and syphilis in St. Petersburg
The purpose statement is to analyze the socio-demographic, clinical, epidemiological, and behavioral characteristics of patients with only HIV infection and those co-infected with HIV and Tr. pallidum, which are under supervision in St. Petersburg GBUZ «Center for the Prevention and Control of AIDS and Infectious Diseases».Material and methods. The data of outpatient cards of 588 patients who were registered in the dispensary at the St. Petersburg Central Clinical Center in the period from 2018 to 2020 were studied, and the data of the cards of males (435 people) were selected. Patients were divided into two groups: with HIV monoinfection (198 people) and with a combination of HIV infection and syphilis (237 people).Results. Patients co-infected compared with HIV-only patients were less likely to have higher education, were less likely to be married, were diagnosed with HIV infection more often at self-report and during routine examination, there were more men who hade sex with men (homosexual), and bisexual men. Co-infected patients were less likely to have used drugs in the present or in the past and were primarily infected with HIV through sexual contact. They were diagnosed mainly with early forms of syphilis. In patients with coinfection, concomitant diseases of the kidneys, cardiovascular, endocrine systems were often detected, and a high comorbidity with chronic hepatitis B was also noted.Conclusion. The identified socio-demographic, clinical, epidemiological and behavioral characteristics of men with HIV + syphilis coinfection indicate the need for more active work aimed at popularizing barrier contraception among men, especially MSM and prone to bisexual contacts; when syphilis is detected in HIV-infected patients, conduct a thorough examination of all organs and systems, extraordinary for the presence of viral hepatitis. 
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来源期刊
HIV Infection and Immunosuppressive Disorders
HIV Infection and Immunosuppressive Disorders Medicine-Infectious Diseases
CiteScore
0.70
自引率
0.00%
发文量
37
期刊介绍: In the scientific-practical journal "HIV Infection and Immunosuppressive Disorders", published various issues of HIV medicine (epidemiology, molecular mechanisms of pathogenesis to the development of educational programs) leading scientists of Russia and countries of CIS, USA, as well as practical healthcare professionals working in research centers, research institutes, universities, clinics where done basic medical work. A special place on the pages of the publication is given to basic and clinical research, analytical reviews of contemporary and foreign reports, the provision of medical care for various diseases.
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