家禽致密骨组织中选择蛋白质的重要性

IF 0.6 Q4 FOOD SCIENCE & TECHNOLOGY Journal of microbiology, biotechnology and food sciences Pub Date : 2023-06-22 DOI:10.55251/jmbfs.10083
M. Steinerova, Š. Nedomová, P. Sláma, A. Pavlík
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引用次数: 0

摘要

在现代家禽品系中,骨骼的完整性受到越来越多的遗传和生产压力的影响,这在许多情况下导致骨骼系统的各种健康问题,包括骨质疏松症和骨折的发展。遗传学在骨完整性中的作用已被几项研究证明,而从基因(即在骨代谢中起重要作用的蛋白质)的靶向研究中获得的知识对骨骼健康具有重要价值,并可能为导致骨骼衰弱的疾病的生物学过程提供新的线索。除了总结骨代谢的基本知识外,本文还介绍了致密骨组织中蛋白质的结构和功能,重点介绍了非胶原蛋白和参与骨代谢信号通路的基因编码的蛋白质。
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IMPORTANCE OF SELECTED PROTEINS OF COMPACT BONE TISSUE IN POULTRY
Within modern poultry lines, the integrity of the skeleton is subjected to increasing genetic and production stress, which in many cases leads to different health problems of the skeletal system, including problems with osteoporosis and the development of fractures. The role of genetics in bone integrity has been demonstrated by several studies, while the knowledge gained from the targeted study of genes, i.e., proteins that play an important role in bone metabolism, is of great value both for skeletal health and may provide new clues to the biological processes underlying diseases leading to the weakening of the bones. In addition to summarizing basic knowledge about bone metabolism, this review provides insight into the structure and function of proteins that are part of compact bone tissue, focusing on non-collagenous proteins and proteins that are encoded by genes involved in signaling pathways that play an important role in bone metabolism.
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来源期刊
CiteScore
1.90
自引率
0.00%
发文量
156
审稿时长
8 weeks
期刊介绍: The Journal of Microbiology, Biotechnology and Food Sciences is an Open Access, peer-reviewed online scientific journal published by the Faculty of Biotechnology and Food Sciences (Slovak University of Agriculture in Nitra). The major focus of the journal is regular publishing of original scientific articles, short communications and reviews about animal, plant and environmental microbiology (including bacteria, fungi, yeasts, algae, protozoa and viruses), microbial, animal and plant biotechnology and physiology, microbial, plant and animal genetics, molecular biology, agriculture and food chemistry and biochemistry, food control, evaluation and processing in food science and environmental sciences.
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