1型糖尿病儿童龋齿的最新进展

IF 0.6 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pediatric Dental Journal Pub Date : 2022-08-01 DOI:10.1016/j.pdj.2022.05.001
Isaac He , Gabrielle Smart , Brianna F. Poirier , Sneha Sethi , Emilija D. Jensen
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引用次数: 1

摘要

1型糖尿病(T1D)是一种慢性自身免疫性疾病,通常在儿童期表现为胰岛素缺乏和由此引起的高血糖。近几十年来,对T1D发病机制的了解有所提高,目前认为是个体遗传、环境、微生物组和免疫系统之间复杂的相互作用。T1D的口腔并发症包括牙周病、口干症和粘膜改变,早期证据表明与龋齿有关。患有T1D的儿童龋齿会导致严重的并发症,包括睡眠质量差、表现和出勤率下降以及口腔摄入量减少。有初步证据表明,较差的血糖控制与较高的龋齿发生率有关。材料和方法对文献进行了批判性的回顾,以假设发病机制并探索T1D与龋齿之间存在的潜在关系。结论血糖控制较差的T1D患儿患龋风险增加。需要进一步的研究来确定血糖控制和口腔微生物群之间是否存在关联。
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An update on dental caries in children with type 1 diabetes mellitus

Introduction

Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease that commonly manifests in childhood as insulin deficiency and resultant hyperglycaemia. Improved understanding of the pathogenesis of T1D has occurred in recent decades and is currently considered to be complex interaction between an individual's genetics, environment, microbiome, and immune system. Oral complications of T1D include periodontal disease, xerostomia, and mucosal changes and early evidence suggesting an association with dental caries. Caries in children with T1D can lead to serious complications including poor sleep quality, reduced performance and attendance at school, and decreased oral intake.There is preliminary evidence suggesting that poorer glycaemic control is related to a higher experience of caries.

Materials and methods

A crtical review of the literature was undertaken to hypothesise the pathogenesis and explore the presence of a potential relationship between T1D and caries.

Conclusion

Children with T1D who have poorer glycaemic control face an increased risk of caries experience. Further research is required to determine if there is an association between glycaemic control and oral microbiota.

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来源期刊
Pediatric Dental Journal
Pediatric Dental Journal DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
1.40
自引率
0.00%
发文量
24
审稿时长
26 days
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