用Fricke凝胶剂量计验证IMRT光束输送的初步研究

Afam Uzorka, J. Bale, David Kibirige
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引用次数: 1

摘要

调强放射治疗(IMRT)的目标是向肿瘤提供均匀剂量,使靶标周围的边缘最小,以增加对疾病的局部控制,同时减少继发性影响。在这项工作中进行的研究表明,Fricke-gel剂量计作为一种质量保证(QA)工具的潜在用途,可以验证由逆治疗计划产生的IMRT治疗。首先,成功地将3D集成Fricke-gel剂量计与公认的剂量测量工具进行了比较。然后测量具有多个方形或矩形场的简单治疗方案和特定逆计划IMRT治疗方案的相对三维剂量分布。通过将CT解剖信息和平面等高线与凝胶测量数据相结合,除了测量平面的剂量-体积直方图(DVH)外,还可以在CT上显示测量剂量和测量等剂量线的等高线。这证明了凝胶剂量计作为IMRT和逆计划的QA工具的实用性。
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Preliminary Study on the Use of Fricke Gel Dosimeter for Verification of IMRT Beam Delivery
The goal of intensity-modulated radiation therapy (IMRT) is to deliver a uniform dose to the tumor with minimal margins around the target, in order to increase local control of the disease while reducing secondary effects. The research performed in this work has shown the potential usefulness of the Fricke-gel dosimeter as a quality assurance (QA) tool to verify IMRT treatments produced by inverse treatment planning. First, the 3D integrating Fricke-gel dosimeter was successfully compared to an accepted dosimetric tool. It was then used to measure relative 3D dose distributions of simple treatment plans with multiple square or rectangular fields and specific inverse-planned IMRT treatment plans. By combining the CT anatomical information and the plan contours with the gel-measured data, it was possible to display the contours on the measured dose and the measured isodose lines on the CT, in addition to measuring dose-volume histograms (DVH) for the plans. This demonstrated the usefulness of the gel dosimeter as a QA tool for IMRT and inverse planning.
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