Clinicopathological Study of Carcinoma Larynx

Setting: Department of otolaryngology and Head-Neck surgery, Rajshahi Medical College Hospital, Rajshahi. Methods: 80 patients were included in this study during a period of July 2006 to June 2007. Study based on history, clinical, radiological, laboratory and histopathological examination. The larynx is divided for purpose of tumour classification into three regionsSupraglottic, Glottic and Subglottic. Results: The age ranges from 25 to 85 years. The overall male to female ratio 93.75:6.25. Laryngeal carcinoma shows significant association with low socioeconomic and education group. The commonest symptoms of laryngeal carcinoma was change of voice 100%(20) in case of glottic carcinoma and 90%(54)in cases of supraglottic carcinoma.Other common symptoms were difficulty of swallowing, respiratory distress, cough, neck swelling, haemoptysis, neck pain. Palpable cervical lymph node was present in 50% (40) cases Conclusion: Predominant histological type was squamous cell carcinoma 97.5%(78), undifferentiated carcinoma 1.25%(1), adenocarcinoma 1.25%(1). Symptoms of presentation has a significant association with site of involvement. The symptoms of presentation of supraglottic carcinoma occurred more frequently at the advanced stage.