人类免疫缺陷病毒1型感染血清和血浆病毒载量测定的比较

IF 1.6 Q4 INFECTIOUS DISEASES Journal of clinical virology plus Pub Date : 2023-02-01 DOI:10.1016/j.jcvp.2022.100127

Lina Mouna, Coralie Pallier, Stephanie Proust, Anne-Marie Roque-Afonso

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引用次数: 0

摘要

人类免疫缺陷病毒1型（HIV）感染的诊断依赖于病毒核酸检测（NAT）。HIV病毒载量（VL）通常在血浆样本中测量。我们评估并比较了血浆HIV VL结果与使用血清样本获得的结果，目的是在没有血浆的紧急情况下使用血清。我们的研究结果表明，在血浆和血清中获得的HIV VL结果之间存在非常高的相关性。

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Comparison of serum and plasma viral load measurements in human immunodeficiency virus type 1 infection

The diagnosis of human immunodeficiency virus 1 (HIV) infections is reliant on viral nucleic acid testing (NAT). HIV viral load (VL) is generally measured in plasma samples.

We evaluated and compared plasma HIV VL results with those obtained using serum samples, the aim being to enable the use of serum in urgent contexts where plasma is not available. Our findings indicated a very high correlation between the HIV VL results obtained in plasma and in serum.

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