Strength training with blood flow restriction in HIV patients positive: a case study

This study purposed to compare responses of segmented neutrophils, monocytes,lymphocytes, and T lymphocyte Clusters of Differentiation 4 and 8 (CD4+ T andCD8+ T) to blood flow restriction training in HIV patients. Two HIV patientsparticipated in the study, one patient had a sedentary lifestyle, and the other wasphysically active. HIV-infected female patients performed a blood flow restrictiontraining session consisting of two exercises: flat bench press and knee extension.Blood (6 mL) was collected for analysis prior to training, immediately aftertraining, and 30 minutes after. After blood flow restriction training, percentagechanges in the number of leukocytes were observed in both patients. Monocytesshowed different responses in the two patients: a decrease in monocyte count wasseen in the physically active, and an increase was observed in the sedentarylifestyle. Lymphocytes showed a higher increase in the physically active than in thesedentary lifestyle. There was an increase in the CD4+ / CD8+ T lymphocyte ratioin both patients. It was concluded blood flow restriction promoted acuteinflammation after training, shown by changes in immune cell counts. Thesechanges did not promote immunosuppression; instead, an increase in CD4+/CD8+T lymphocyte ratio was observed; and HIV-infected came similar results. Keywords: muscle strength; acquired immune deficiency syndrome; HIV-1; exercise; Kinanthropometry