In order to explore the feasibility of using kitchen waste wastewater as a fermentation substrate to produce liquid potassium solubilizing bacterial fertilizer, Bacillus mucilaginosus was selected as the experimental strain, and the relevant growth factors were optimized using orthogonal and single factor methods. The results showed that after a 3-day adjustment period, Bacillus mucilaginosus entered a logarithmic growth phase when cultured in kitchen waste water, and the maximum viable bacterial count was reached at 6-7 days, The number of viable bacteria in Class I wastewater is 1.55 × 10 10 CFU/mL, Class II wastewater with a viable bacterial count of 6.60 × 10 10 CFU/mL. The optimal cultivation conditions determined by orthogonal experiments using Class II wastewater as the substrate were pH=7, temperature 30 ℃, shaking speed 160 r/min, and inoculation amount 2.0% (V/V). The pH and salt content of the wastewater had a significant impact on the growth and metabolism of Bacillus cereus: the optimal initial pH was 7 (with a viable bacterial count of 3.80) × 10 10 CFU/mL and 9.20 × 10 10 CFU/mL); With ρ The increase of (NaCl) leads to a rapid decrease in the number of viable bacteria, which is most suitable ρ The optimal inoculation amount for Class I and Class II wastewater with a NaCl concentration of 4 g/L. is 1.5% (with a viable bacterial count of 1.60), respectively × 10 10 CFU/mL) and 2.0% (6.40 viable bacteria) × 10 10 CFU/mL). Studies have shown that after cultivation in kitchen waste wastewater, Bacillus gelatinosus can reach the live bacterial count (2.0) of liquid microbial fertilizer in GB 20287-2006 "Agricultural Microbial Agents" × 10 8 CFU/mL), Class II wastewater treated with damp heat has a significant promoting effect on the growth of Bacillus cereus