冷加压超反应年轻男性的血压和心率恢复

Suzanna Adnan, F. Neda, Bassam Al-Gailani
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摘要

导语:冷压试验(CPT)的过度心血管反应(超反应)可以预测以后是否会发生高血压。本研究旨在评估CPT过程中血压(BP)和心率(HR)的变化情况以及压力刺激后的恢复情况。受试者与方法:34名受试者将左手浸泡在冷水中2分钟,记录在冰水浸泡试验期间和试验结束后3分钟(间隔1分钟)血压和心率的变化。血压变化结果用平均血压(MBP)表示。如果血压变化(Δsystolic BP/Δdiastolic BP)≥22/18 mm,志愿者对CPT的反应被归类为超反应。结果:收缩期高反应组(SHR)和舒张期高反应组(DHR)的MBP在CPT结束后较正常反应组(NRs)维持较长时间(3min)的高水平(分别为20%和25%)。DHR组NR患者CPT后MBP无变化。在两组心率(即SHR和DHR)中观察到相同的一般行为。结论:超反应器的特点是MBP和HR的显著升高,MBP和HR恢复到基线水平的时间较长。
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Blood pressure and heart rate recovery in cold pressor hyper-reactor young males
Introduction: The exaggerated cardiovascular response (hyper-reaction) to the cold pressor test (CPT) can predict whether hypertension will develop later on. The study aims to assess the profile blood pressure (BP) and heart rate (HR) changes during CPT and the recovery from the pressor stimulus. Subjects and Methods: Thirty-four participants were asked to immerse their left hand in chilly water for 2 min, and the pressor response in terms of BP and HR changes during the ice-cold water immersion test and for 3 min (at 1-min interval) after the cessation of the test was recorded. The result of BP changes was expressed as a mean BP (MBP). The volunteer responses to CPT were classified as hyper-reactants if the change in BP (Δsystolic BP/Δdiastolic BP) was ≥22/18 mm. Results: The MBP of the systolic hyper-reactor (SHR) and diastolic hyper-reactor (DHR) volunteers was sustained at significantly high levels (by 20% and 25%, respectively) for a longer time (3 min) after the end of CPT relative to normal reactors (NRs). There was no change in MBP upon CPT in NR within the DHR group. The same general behavior was observed with heart rate in both groups (i.e. SHR and DHR). Conclusion: The hyper-reactors are characterized by an exaggerated increase in MBP and HR and a longer time for the MBP and HR to return to their baseline levels.
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