脑淀粉样血管病相关炎症:美国神经放射学会2020年度病例

Q4 Medicine Neurographics Pub Date : 2022-04-01 DOI:10.3174/ng.2100028
G. Kadam, S. Supple, M. Jhaveri
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引用次数: 1

摘要

脑淀粉样血管病相关炎症(CAARI)是一种急性/亚急性脑病综合征。目前,虽然淀粉样蛋白沉积和由此产生的血管周围炎症和细胞浸润被认为是潜在的原因,但这种实体的潜在发病机制尚不清楚。对CAARI的明确诊断可能需要进行脑活检,这在临床上并不总是可行的。此外,CAARI对实质的影响并不均匀,活检有时可能出现假阴性。当出现时,结合有用的影像学发现和高怀疑指数可能有助于避免与侵入性脑活检相关的发病率,并建立及时的诊断。本文描述了CAARI常见的影像学和临床表现之一。
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Cerebral Amyloid Angiopathy‐related Inflammation: American Society of Neuroradiology 2020 Case of the Year
Cerebral amyloid angiopathy‐related inflammation (CAARI) presents as a syndrome of acute/subacute encephalopathy. Currently, the underlying etiopathogenesis of this entity is not well established, though the amyloid deposits and resulting perivascular inflammation and cellular infiltrate are said to be the underlying cause. A definitive diagnosis of CAARI may require brain biopsy, which is not often clinically feasible in every case. Furthermore, CAARI does not affect the parenchyma uniformly, and biopsy could be falsely negative at times. When present, the combination of helpful imaging findings and a high index of suspicion may help avoid the morbidity associated with invasive brain biopsy and establish a timely diagnosis. This article describes one of the commonly encountered imaging and clinical presentations of CAARI.
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来源期刊
Neurographics
Neurographics Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
0.20
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0.00%
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12
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