印度高血压管理中的患者依从性、合并症和挑战

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL International Journal of Noncommunicable Diseases Pub Date : 2022-10-01 DOI:10.4103/jncd.jncd_72_22
Prateek Singh, T. Dilip
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引用次数: 0

摘要

背景和目的:截至目前,印度只有三分之一的高血压患者不知道这种情况的存在,只有极少数确诊患者可以通过药物控制。有必要了解接受高血压治疗的患者的特征和行为,为更好地管理这种情况提供证据。在这种情况下,该研究考察了与高血压药物治疗患者血压(BP)水平失控相关的关键因素。主题和方法:2017-18年印度具有全国代表性的纵向老龄化研究调查数据用于分析。这项研究仅限于12353名45岁及以上的受访者,他们在调查前已经被诊断为高血压,正在接受药物治疗。调查时的血压水平用于将受访者分为受控高血压(收缩压<140 mm和舒张压<90 mm)、1级高血压(收缩14–159 mm或舒张90–99 mm)、2级高血压(收缩期160–179 mm或舒张100–109 mm)和3级高血压(缩缩缩180或以上mm或舒张110或以上mm)。进行双变量和多变量逻辑回归分析,以研究这些患者的高血压控制与其人口统计学、社会经济和行为特征之间的关系。结果:尽管服用了药物,但仍有相当比例的受访者患有1级(31%)、2级(15%)和3级(2%)的未控制高血压。与其他人群相比,农村地区高血压失控的风险较高(比值比[OR]=1.37,95%置信区间[CI],P<0.01)、独居老年人(OR=1.63,95%CI,P<0.05)、没有上学的患者(OR=1.18,95%CI)、肥胖患者(OR=1.2,95%CI,酗酒者(OR=1.6,95%CI,P<0.01)。解释和结论:来自农村地区、最贫穷和最脆弱地区的患者对血压水平的控制不力,支持了政府自2018年以来为扩大非传染性疾病(包括高血压)的社区筛查和供应所做的努力。此外,在接受高血压药物治疗的患者中,具体努力促进健康对于更好地管理这种情况也至关重要。
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Patient compliance, comorbidities, and challenges in the management of hypertension in India
Background and Objectives: As of now, only one-third of those with hypertension in India are unaware of the existence of this condition, and only a negligible share of those diagnosed can control it through medication. There is a need to understand the characteristics and behaviors of patients treated for hypertension for generating evidence for better management of this condition. In this context, the study examines the key factors associated with uncontrolled blood pressure (BP) levels in patients under medication for hypertension. Subject and Methods: Data from the nationally representative Longitudinal Ageing Study of India survey, 2017–18, are used for the analysis. This study is restricted to 12,353 respondents aged 45 years and above who were already diagnosed with hypertension before the survey and are under medication. BP level at the point of the survey was used to classify the respondents as hypertension under control (systolic <140 mm and diastolic <90 mm), Grade-1 Hypertension (systolic 14–159 mm or diastolic 90–99 mm), Grade-2 Hypertension (systolic160–179 mm or diastolic 100–109 mm), and Grade-3 Hypertension (systolic 180 or above mm or diastolic 110 or above mm). Bivariate and multivariate logistic regression analysis is performed to study the association between hypertension control in these patients and their demographic, socioeconomic, and behavioural characteristics. Results: A critical proportion of respondents have uncontrolled hypertension of Grade 1 (31%), Grade 2 (15%), and Grade 3 (2%), despite taking medication for the same. As compared to their remaining counterparts, the risk of uncontrolled hypertension is high in rural areas (odds ratio [OR] = 1.37, 95% confidence interval [CI], P < 0.01), old-adults living alone (OR = 1.63, 95% CI, P < 0.05), patients having no schooling (OR = 1.18, 95% CI, P < 0.05), patients with obesity (OR = 1.2, 95% CI, P < 0.05), moderate alcohol drinkers (OR = 2.1, 95%CI, P < 0.01), abusive alcohol drinkers (OR = 1.6, 95% CI, P < 0.01). Interpretation and Conclusions: Poor control over BP levels among patients from rural areas, the poorest and most vulnerable sections, supports the governmental efforts initiated since 2018 to expand community-level screening and provisioning of noncommunicable diseases, including that for hypertension. In addition, concrete efforts for health promotion within patients under medication for hypertension too are essential for better management of this condition.
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