人类嗜t淋巴病毒1型在脑死亡器官捐献者中的流行

IF 0.5 Q4 INFECTIOUS DISEASES Archives of Clinical Infectious Diseases Pub Date : 2022-07-30 DOI:10.5812/archcid-116005

E. Nasri, H. Fakhim, Abolfazl Jafari-Sales, Hossein Bannazadeh Baghi, A. Vaezi, M. Rezaei, P. Tabarsi

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引用次数: 0

摘要

目的：本研究旨在评估伊朗德黑兰Masih Daneshvari医院脑死亡器官捐献者中人类嗜T淋巴细胞病毒1型（HTLV-1）的患病率。方法：采用酶联免疫吸附试验（ELISA）对54名器官捐献者进行HTLV-1病毒的横断面研究。随后，进行蛋白质印迹确认以确认HTLV-I感染。结果：在54例ELISA检测的患者中，2例（3.4%）检测到抗-HTLV-1抗体。在阳性结果的病例中进行了蛋白质印迹，但没有一名受试者的HTLV-1感染检测呈阳性。结论：本研究的结果表明，脑死亡器官捐献者中HTLV-I感染的病例非常罕见。然而，建议对器官捐献者进行这种病毒流行率的调查。

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Prevalence of Human T-Lymphotropic Virus Type 1 in Brain-Dead Organ Donors

Objectives: This study aimed to assess the prevalence of human T-lymphotropic virus type 1 (HTLV-1) among brain-dead organ donors at Masih Daneshvari Hospital in Tehran, Iran. Methods: By enzyme-linked immunosorbent assay (ELISA), 54 organ donors were screened for HTLV-1 virus in this descriptive cross-sectional study. Following that, Western blot confirmation was performed to confirm the HTLV-I infection. Results: Anti-HTLV-1 antibodies were detected in 2 (3.4%) cases out of 54 patients tested by ELISA. A western blot was performed in cases of positive results, but none of the subjects tested positive for HTLV-1 infection. Conclusions: The results of the present study indicated rare cases of HTLV-I infection in brain-dead organ donors. However, it is recommended that organ donors be investigated for the prevalence of this virus.

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来源期刊

Archives of Clinical Infectious Diseases INFECTIOUS DISEASES-

CiteScore

3.40

自引率

0.00%

发文量

期刊介绍： Archives of Clinical Infectious Diseases is a peer-reviewed multi-disciplinary medical publication, scheduled to appear quarterly serving as a means for scientific information exchange in the international medical forum. The journal particularly welcomes contributions relevant to the Middle-East region and publishes biomedical experiences and clinical investigations on prevalent infectious diseases in the region as well as analysis of factors that may modulate the incidence, course, and management of infectious diseases and pertinent medical problems in the Middle East.